Basic information
- CAS
97468-37-6- Standard SMILES
CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CSc3ccncc3)[C@H]2SC1.CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CSc3ccncc3)[C@H]2SC1.c1ccc(CNCCNCc2ccccc2)cc1- InChIKey
JAHKOXGROZNHHG-RACYMRPCSA-N- Molecular formula
- C50H54N8O12S4
- Average molar mass
- 1,087.3 g/mol
- Monoisotopic mass
- 1,086.27440388
Overview
Cephapirin Benzathine is the benzathine salt form of cephapirin, a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity. Cephapirin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.
Names & identifiers
- Preferred name
- Cephapirin Benzathine
- IUPAC
- bis((6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid);N,N'-dibenzylethane-1,2-diamine
- English name
- Cephapirin benzathine
- Molecular formula
- C33H37N5O6S2
- Molecular weight
- 663.81
Names & synonyms
Cephapirin benzathineCefapirin benzathineToMORROWToMORROW intramammary infusionUNII-90G868409OCephapirin benzathine (USP)Cephapirin benzathine [USP]90G868409O(6R,7R)-3-(Hydroxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid compound with N,N'-dibenzylethylenediamine (2:1)CEPHAPIRIN COMPD WITH N,N'-DIBENZYLETHYLENEDIAMINECEPHAPIRIN BENZATHINE (USP-RS)CEPHAPIRIN BENZATHINE [USP-RS]
Show more names
Benzyl ceftimeBenzathine cefpirinEPHAPIRINBENZATHINE(100MG)CEPHAPIRINBENZATHINE(100MG)Cephapirin Benzathine (1102408)Cephapirin Benzathine, 10 mM in DMSO(6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-{[(pyridin-4-ylsulfany...(6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CEPHAPIRIN BENZATHINE (USP IMPURITY)CEPHAPIRIN BENZATHINE [USP IMPURITY]CEPHAPIRIN BENZATHINE (USP MONOGRAPH)CEPHAPIRIN BENZATHINE [USP MONOGRAPH]Cefa-DriRefChem:5475097468-37-6Metricure
Properties
Computed structural properties
- Topological polar surface area
- 377 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 20
- Rotatable bonds
- 23
- Heavy atoms
- 74
- Formal charge
- 0
- Complexity
- 878
Experimental & physicochemical properties
Animal DrugsFDA approved animal drugs -> Active ingredient
Physicochemical properties
- Melting point
- 166 · 166-170°C (dec.)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- DMSO (Slightly)
- form
- Solid
- color
- Pale Beige to Light Brown
- FDA UNII
- 90 G868409O · 90G868409O
- Symbol(GHS)
- 8 · GHS08
- Signal word
- Danger
- Hazard statements
- 317 · H317-H334
- Precautionary statements
- 261 · P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501
- HS Code
- 2941906000 · 2941906000
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Hazard information
Regulatory InformationCephapirin benzathine: Does not have an individual approval but may be used under an appropriate group standard
Safety data
- hs_code
- 2941906000
- Signal word
- Danger
- Symbol(GHS)
- GHS08
- Hazard statements
- H317-H334
- Precautionary statements
- P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P261-P285-P304+P341-P342+P311-P501
Chemistry & industry
Applications
UsesCephapirin Benzathine is used in the treatment of animals suffering from bacterial infections. Used in cattle in the treatment of inflammation of the uterus or endometritis. Antibacterial.
UsesCephapirin Benzathine is used in the treatment of animals suffering from bacterial infections. Used in cattle in the treatment of inflammation of the uterus or endometritis. Antibacterial.
Suppliers100 total
山东玖玥生物科技有限公司15553333686 · [email protected]
国药集团化学试剂有限公司86-21-63210123 · [email protected]
上海沛灵生物科技有限公司13127581762 13127581762 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
武汉英诺医药科技有限公司+86-027-59232304 15387063101 · [email protected]
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
山东海舟生物工程有限公司130-0567-0367 13006570367 · [email protected]
清宁生物（江苏博泉生物科技有限公司）王 19352250998 13160238781 · [email protected]
湖北海克斯生化有限公司17362916295; 17362916295 · [email protected]
武汉灵灵九生物科技有限公司15623309010 · [email protected]
湖北海克斯生化有限公司18696113233 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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