Growth hormone, human
HGH · SOMATROPIN · GH · GROWTH HORMONE · SH · phyol · GROWTH HORMONE, HUMAN PITUITARY · GH (hormone)
Identifiers & Physical Properties
| CAS No. | 9002-72-6 |
|---|---|
| Molecular formula | C72H132 |
| Average molar mass | 997.8 g/mol |
| Monoisotopic mass | 997.03290421 g/mol |
| SMILES | CC(C)(C)C1C=CCCCCC1.CC(C)(C)C1C=CCCCCC1.CC(C)(C)C1CC=CCCCC1.CC(C)(C)C1CC=CCCCC1.CC(C)(C)C1CCC=CCCC1.CC(C)(C)C1CCC=CCCC1 |
| InChIKey | JBUMAHXQYQFIDW-UHFFFAOYSA-N |
| PubChem CID | 168009821 |
| EC No. | 232-666-5 |
Chemical & Physical Properties
| Topological polar surface area | 0 |
|---|---|
| Hydrogen bond donors | 0 |
| Hydrogen bond acceptors | 0 |
| Rotatable bonds | 6 |
| Heavy atoms | 72 |
| Formal charge | 0 |
| Complexity | 444 |
| Chemical classes | Other Uses -> Pharmaceuticals |
| Storage conditions | 2-8°C |
| Solubility | ethanolamine: 5mg/mL (basic buffers, pH 9-10) |
| Physical state | lyophilized powder |
| Biological source | chicken |
| Cosmetics Ingredients Functions | ANTI-SEBUMSKIN PROTECTING |
| UNSPSC Code | 51111800 |
| NACRES | NA.32 |
| Hazard symbols | B |
| Water hazard class (WGK) | 3 |
| RTECS number | TO7385000 |
| Customs code | 3504009000 |
| Storage class | 13 - Non Combustible Solids |
| Toxicity | TDLo parenteral in child: 300ug/kg/6D-I |
Safety & Regulations
| Regulatory information | Somatotropin (porcine): Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
|---|---|
| Hazards summary | A small peptide hormone released by the anterior pituitary under hypothalamic control. Somatotropin, or growth hormone, stimulates mitosis, cell growth, and, for some cell types, differentiation in many tissues of the body. It has profound effects on many aspects of gene expression and metabolism. [ChemIDplus] |
| Water hazard class (WGK) | 3 |
| RTECS number | TO7385000 |
| Customs code | 3504009000 |
| Toxicity | TDLo parenteral in child: 300ug/kg/6D-I |
| Hazard symbols | B |
| Storage class | 13 - Non Combustible Solids |
Applications & Uses
Uses
Somatotropin (STH) has been used to study its effects on repressing hepatic H2S production post-transcriptionally. It has also been used as one of the components of a medium to culture primordial follicles.
General Description
Somatotropin or growth hormone is a peptide hormone that is secreted by the anterior pituitary gland. It is essential for growth. The hormone increases muscle mass, reduces fat mass, helps in maintaining normal blood glucose levels and also promotes a balanced lipid profile.
Description
GH Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids and having a molecular mass of 22kDa. Growth Hormone is purified by proprietary chromatographic techniques.