HuagongsheHuagongshe Chemistry Print Report · For research reference only
Percoll
abs9102 · PERCOLL · PERCOLL(R) · CENTRICOLL · PERCOLL(TM) · CENTRICOLL(TM) · Percoll (1.131) · PERCOLL(R)(2-8℃)
Identifiers & Physical Properties
| CAS No. | 65455-52-9 |
|---|---|
| Molecular formula | C186H243N29O26S6 |
| Average molar mass | 3,493 g/mol |
| Monoisotopic mass | 3,490.690836 g/mol |
| SMILES | CC(CO)CNC(=O)C(C#N)=Cc1ccc(N(C)C)cc1.CC(CO)CNS(=O)(=O)C(C#N)=Cc1ccc2cc(N3CCCCC3)ccc2c1.CC(CO)CNS(=O)(=O)C(C#N)=Cc1ccc2cc(N3CCN(C)CC3)ccc2c1.CC(CO)CNS(=O)(=O)C(C#N)=Cc1ccc2cc(N3CCOCC3)ccc2c1.CC(CO)CNS(=O)(=O)C(C#N)=Cc1ccc2cc(NCCN3CCOCC3)ccc2c1.CCCN(CCC)c1ccc(C=C(C#N)C(=O)NCC(C)CO)cc1.CCCN(CCC)c1ccc2cc(C=C(C#N)S(=O)(=O)NCC(C)CO)ccc2c1.CCN(CC)c1ccc(C=C(C#N)C(=O)NCC(C)CO)cc1.CCN(CC)c1ccc2cc(C=C(C#N)S(=O)(=O)NCC(C)CO)ccc2c1 |
| InChIKey | RZPNYVYWMSGMNL-UHFFFAOYSA-N |
| PubChem CID | 168009829 |
| EC No. | 306-819-2 |
Chemical & Physical Properties
| Topological polar surface area | 874 |
|---|---|
| Hydrogen bond donors | 19 |
| Hydrogen bond acceptors | 52 |
| Rotatable bonds | 75 |
| Heavy atoms | 247 |
| Formal charge | 0 |
| Complexity | 5,640 |
| Polymers | Plastics & Rubber -> Polymers |
| Cosmetics | Skin conditioning |
| Physical Description | White odorless suspension[Research Organics MSDS] |
| Density | 1.1 g/mL at 25 °C(lit.) |
| Storage conditions | 2-8°C |
| Color | clear colorless to faint yellow |
| pH | 8.9 (20°C) |
| UNSPSC Code | 12352207 |
| NACRES | NA.75 |
| Water hazard class (WGK) | 3 |
Safety & Regulations
| Hazards summary | May cause irritation[Research Organics MSDS] |
|---|---|
| Protective Action Criteria (PAC) | 30 [mg/m3]330 [mg/m3]2000 [mg/m3] |
| Water hazard class (WGK) | 3 |
Applications & Uses
Uses
Percoll consists of colloidal silica particles of 15-30 nm diameter (23% w/w in water) which have been coated with polyvinylpyrrolidone (PVP). It is used to establish non-toxic low viscosity, low osmolarity density gradients that can be used to isolate cells, organelles and viruses. It has been used to separate inner and outer membrane vesicles from E. coli. Percoll is isosmotic throughout the gradient, non-toxic, and is easily removed from the purified materials.