HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glutamate Dehydrogenase
GLDH · GLDH USP/EP/BP · Glutamate dehydrogenase 1 · glutamic acid dehydrogenase · Naphthoic Acid Impurity 106 · Glutamic acid dehydrogenase 1 · L-Glutamic acid dehydrogenase · NAD(P)-glutamate dehydrogenase
Identifiers & Physical Properties
| CAS No. | 9001-46-1 |
|---|---|
| Molecular formula | C24H46N2O |
| Average molar mass | 378.6 g/mol |
| Monoisotopic mass | 378.3610141 g/mol |
| SMILES | C=CC=C(C=C)C(C)NCC(O)CNC(C)C(C=CC)=CCC.CC.CC |
| InChIKey | IBHGHYUWZKCMRA-UHFFFAOYSA-N |
| PubChem CID | 168009864 |
| EC No. | 232-607-3 |
Chemical & Physical Properties
| Topological polar surface area | 44.3 |
|---|---|
| Hydrogen bond donors | 3 |
| Hydrogen bond acceptors | 3 |
| Rotatable bonds | 12 |
| Heavy atoms | 27 |
| Formal charge | 0 |
| Complexity | 435 |
| Chemical classes | Biological Agents -> Enzymes |
| Physical Description | Off-white powder[Sigma-Aldrich MSDS] |
| Storage conditions | -20°C |
| Physical state | solution (viscous) |
| Color | amber |
| Biological source | bovine liver |
| Specific Activity | ≥40units/mg protein |
| EPA Substance Registry System | Dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)) (9029-12-3) |
| UNSPSC Code | 12352204 |
| NACRES | NA.54 |
| GHS pictogram | GHS08 |
| Signal word | Danger |
| GHS hazard statements | H334 |
| GHS precautionary statements | P261-P284-P501 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 3 |
| F | 3-10 |
| TSCA inventory status | TSCA listed |
| Storage class | 11 - Combustible Solids |
| Hazard class | Resp. Sens. 1 |
Safety & Regulations
| GHS classification | This chemical does not meet GHS hazard criteria for 100% (3 of 3) of all reports.Not ClassifiedAggregated GHS information provided per 3 reports by companies from 1 notifications to the ECHA C&L Inventory.DangerH334 (100%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]P233, P260, P271, P284, P304+P340, P342+P316, P403, and P501 (click each P-code to see the statement) |
|---|---|
| Regulatory information | Chemical: Dehydrogenase, glutamate [nicotinamide adenine dinucleotide(phosphate)]XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).Dehydrogenase, glutamate (nicotinamide adenine dinucleotide (phosphate)): Does not have an individual approval but may be used under an appropriate group standard |
| Other safety information | IMAP assessments - Dehydrogenase, glutamate [nicotinamide adenine dinucleotide(phosphate)]: Environment tier I assessment |
| Hazards summary | May cause irritation[Sigma-Aldrich MSDS] See ENZYMES. |
| Hazard Classes and Categories | Not ClassifiedResp. Sens. 1 (100%) |
| F | 3-10 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 3 |
| TSCA inventory status | TSCA listed |
| Signal word | Danger |
| GHS pictogram | GHS08 |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H334 |
| Hazard class | Resp. Sens. 1 |
| GHS precautionary statements |
Applications & Uses
Uses
L-Glutamic Dehydrogenase was used to catalyzes the conversion of isocitrate into a-ketoglutarate and carbon dioxide.