HuagongsheHuagongshe Chemistry Print Report · For research reference only
Choline oxidase
EC 1.1.3.17 · CHOLINE OXIDASE · Oxidase, choline · 10 units/mg solid · COD Choline oxidase · Choline oxidase（CODA） · Choline Oxidase(CHOO) · Dehydrogenase, choline
Identifiers & Physical Properties
| CAS No. | 9028-67-5 |
|---|---|
| Molecular formula | C42H74N12O9S4 |
| Average molar mass | 1,019.4 g/mol |
| Monoisotopic mass | 1,018.45845668 g/mol |
| SMILES | CNC(CC(=O)OC)C(=O)C=CN.CNC(CSC)C(=O)C=CN.CNC(CSCC(=O)OC)C(=O)C=CN.CNC(CSSc1ccccn1)C(=O)C=CN.CNCC(NC)C(=O)C=CN |
| InChIKey | XOUJHUSVMZWJBZ-UHFFFAOYSA-N |
| PubChem CID | 168009869 |
| EC No. | 232-840-0 |
Chemical & Physical Properties
| Topological polar surface area | 454 |
|---|---|
| Hydrogen bond donors | 11 |
| Hydrogen bond acceptors | 25 |
| Rotatable bonds | 31 |
| Heavy atoms | 67 |
| Formal charge | 0 |
| Complexity | 1,010 |
| Storage conditions | -20°C |
| Physical state | powder |
| Color | yellow |
| Specific Activity | 8-20units/mg solid |
| UNSPSC Code | 12352204 |
| NACRES | NA.54 |
| GHS pictogram | GHS08 |
| Signal word | Danger |
| GHS hazard statements | H334 |
| GHS precautionary statements | P261-P284-P501 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Safety statements (S) | 22-24/25 |
| Water hazard class (WGK) | 3 |
| F | 10-21 |
| Storage class | 11 - Combustible Solids |
| Hazard class | Resp. Sens. 1 |
Safety & Regulations
| GHS classification | DangerH334 (100%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]P233, P260, P271, P284, P304+P340, P342+P316, P403, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 118 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Resp. Sens. 1 (100%) |
| F | 10-21 |
| Personal protective equipment (PPE) | Eyeshields, Gloves, type N95 (US) |
| Water hazard class (WGK) | 3 |
| Signal word | Danger |
| GHS pictogram | GHS08 |
| Safety statements (S) | 22-24/25 |
| Storage class | 11 - Combustible Solids |
| GHS hazard statements | H334 |
| Hazard class | Resp. Sens. 1 |
| GHS precautionary statements | P261-P284-P501 |
Applications & Uses
Uses
Choline oxidase from Alcaligenes sp. has been used in a study to investigate a choline biosensor constructed with chitinous membrane and its application in measuring cholinesterase inhibitory activities. Choline oxidase from Alcaligenes sp. has also been used in spectroscopic studies on the photoreaction of choline oxidase with covalently bound flavin.
Uses
Choline oxidase from Sigma has been used in the enzymatic determination of choline in milk using a flow injection analysis (FIA) system with potentiometric detection.