Basic information
- CAS
106375-28-4- Standard SMILES
C[C@H](O)[C@@H]1NC(=O)[C@H]2C[C@H](O)CN2C(=O)[C@H](CO)NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CSSC[C@@H](N)C(=O)N[C@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N4C[C@H](O)C[C@H]4C(=O)NCC(=O)N[C@H](CO)C(=O)N[C@H](CO)C(=O)N2)NC(=O)[C@@H](CSSC[C@H](C(=O)N[C@H](Cc2ccc(O)cc2)C(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@H]2C[C@H](O)CN2C(=O)[C@H](CC(N)=O)NC3=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CO)NC1=O- InChIKey
FDQZTPPHJRQRQQ-BAZDQHSYSA-N- Molecular formula
- C120H182N38O43S6
- Average molar mass
- 3,037.4 g/mol
- Monoisotopic mass
- 3,035.1547236
Names & identifiers
- Preferred name
- H-D-Cys(1)-D-Lys-Ser-Hyp-Gly-D-Ser-D-Ser-Cys(2)-Ser-D-Hyp-aThr-Ser-Tyr-Asn-D-Cys(3)-D-Cys(1)-Arg-Ser-Cys(2)-Asn-D-Hyp-D-Tyr-Thr-Lys-Arg-D-Cys(3)-D-Tyr-NH2
- IUPAC
- (1R,4S,8S,10R,13S,16S,19S,22S,25S,30S,33S,36S,39S,42R,45R,47S,51S,54R,57S,60S,63S,68S,71R,74S,78R,80S,86R,89R)-68-amino-36,71-bis(4-aminobutyl)-N-[(2R)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-22,51-bis(2-amino-2-oxoethyl)-33,60-bis(3-carbamimidamidopropyl)-8,47,78-trihydroxy-13-[(1S)-1-hydroxyethyl]-39-[(1R)-1-hydroxyethyl]-4,16,57,74,86,89-hexakis(hydroxymethyl)-19,42-bis[(4-hydroxyphenyl)methyl]-2,5,11,14,17,20,23,32,35,38,41,44,50,53,56,59,62,69,72,75,81,84,87,90,97-pentacosaoxo-27,28,65,66,93,94-hexathia-3,6,12,15,18,21,24,31,34,37,40,43,49,52,55,58,61,70,73,76,82,85,88,91,96-pentacosazahexacyclo[52.37.4.225,63.06,10.045,49.076,80]heptanonacontane-30-carboxamide
- English name
- OMEGA-CONOTOXIN GVIA
- Molecular formula
- C120H182N38O43S6
- Molecular weight
- 3037.36
Names & synonyms
106375-28-4OMEGA-CGTX GVIAw-ConotoxinGVIAω-conotoxin gviao-Conotoxin GVIAω-Conotoxin GVIA |OMEGA-CONOTOXIN GVIAOMEGA-CONOTOXIN GVIA ISOMEROMEGA-CONOTOXIN GVIA USP/EP/BPω-Conotoxin GVIA (0.5 mg vial)M.W. 3037.35 C120H182N38O43S6
Database identifiers
- CAS
106375-28-4- PubChem CID
- 169543500
- EC Number
- 686-416-9
Properties
Computed structural properties
- XLogP
- -15.8
- Topological polar surface area
- 1,500 Ų
- Hydrogen bond donors
- 49
- Hydrogen bond acceptors
- 54
- Rotatable bonds
- 39
- Heavy atoms
- 207
- Formal charge
- 0
- Complexity
- 6,820
Physicochemical properties
- Density
- 1.71 · 1.71
- storage temp.
- -20 °C · -20°C
- form
- Lyophilized
- Water Solubility
- 1 mg/ml · Soluble to 1 mg/ml in Water
- FDA UNII
- 0 P8WMJ8Q · AA0P8WMJ8Q
- UNSPSC Code
- 12352202 · 12352202
- NACRES
- 77 · NA.77
- Symbol(GHS)
- 6 · GHS06
- Signal word
- Danger
- Hazard statements
- 311 · H311-H330-H301
- Precautionary statements
- 280 · P280-P302+P352-P312-P322-P361-P363-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501
- PPE
- 95 · Eyeshields, Gloves, type N95 (US)
- RIDADR
- 3172 · 3172
- WGK Germany
- 3 · 3
- RTECS
- 2665050 · GL2665050
- HazardClass
- 6.1 · 6.1(b)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P260, P261, P262, P264, P270, P271, P280, P284, P301+P316, P302+P352, P304+P340, P316, P320, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information.omega.-Conotoxin G VIA: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesAcute Tox. 3 (100%)
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- rtecs
- GL2665050
- ridadr
- 3172
- Signal word
- Danger
- Symbol(GHS)
- GHS06
- hazard_class
- 6.1(b)
- Storage Class
- 11 - Combustible Solids
- packing_group
- III
- Hazard statements
- H311-H330-H301
- Precautionary statements
- P280-P302+P352-P312-P322-P361-P363-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501
Chemistry & industry
Applications
Usesω-Conotoxin GVIA has been used as an antagonist for N-type calcium channel (CaV2.2) in various studies.
Suppliers58 total
深圳市健竹科技有限公司0755-89218110 13480856786 · [email protected]
成都彼样生物科技有限公司18108052721 · [email protected]
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
南京昱盛康生物科技有限公司13327808530 · [email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
上海鸿肽生物科技有限公司15318089928 · [email protected]
武汉易泰科技有限公司上海分公司18930552037 · [email protected]
中科华药(江苏)生物科技有限公司18020125070 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
InvivoChem中国13549236410 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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