Basic information
- CAS
45103-58-0- Standard SMILES
C=C(C)C(=O)OCCOCCOC- InChIKey
DAVVKEZTUOGEAK-UHFFFAOYSA-N- Molecular formula
- C9H16O4
- Average molar mass
- 188.22 g/mol
- Monoisotopic mass
- 188.10485899
Overview
Based on available data, the CIR Expert Panel concluded that... Methoxydiglycol Methacrylate is safe as used in nail enhancement products when skin contact is avoided. Products containing these ingredients should be accompanied with directions to avoid skin contact, because of the sensitizing potential of Methacrylates.
Names & identifiers
- Preferred name
- 2-(Methoxyethoxy)ethyl methacrylate
- IUPAC
- 2-(2-methoxyethoxy)ethyl 2-methylprop-2-enoate
- English name
- 2-(2-Methoxyethoxy)ethyl methacrylate
- Molecular formula
- C9H16O4
- Molecular weight
- 188.22
Names & synonyms
45103-58-02-(2-Methoxyethoxy)ethyl methacrylateMethoxydiglycol methacrylateMDM cpd2-Propenoic acid, 2-methyl-, 2-(2-methoxyethoxy)ethyl ester0548T81DSOBLEMMER PME 100NK ESTER M 20GDTXSID80684642-(methoxyethoxy)ethyl methacrylateRefChem:461184DTXCID0040381
Show more names
DGMEMAMOEOEMA2-Methoxyethoxyethyl MethacrylateMethoxydiethyleneglycol methacrylate2-(2-Methoxyethoxy)ethy methacrylateMethacrylic acid 3,6-dioxaheptane-1-yl ester
256-190-2Diethylene glycol monomethyl ether methacrylate2-(2-methoxyethoxy)ethyl 2-methylprop-2-enoateDi(ethylene glycol) methyl ether methacrylateMethyl Carbitol Methacrylate2-(2-methoxyethoxy)ethylmethacrylateMETHOXYETHOXYETHYL METHACRYLATEMFCD00059330
Database identifiers
- CAS
45103-58-0- PubChem CID
- 170752
- DTXSID
Properties
Computed structural properties
- XLogP
- 0.9
- Topological polar surface area
- 44.8 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 8
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 165
Experimental & physicochemical properties
CosmeticsCosmetic ingredients (Methoxydiglycol Methacrylate) -> CIR (Cosmetic Ingredient Review)
Physicochemical properties
- Boiling point
- 98 °C/3.5 · 98 °C/3.5 mmHg (lit.)
- Density
- 1.02 g/mL · 1.02 g/mL at 25 °C (lit.)
- vapor pressure
- 3.19 Pa · 3.19Pa at 20℃
- refractive index
- 20 · n20/D 1.44(lit.)
- Flash point
- 230 °F · >230 °F
- storage temp.
- 2 · 2-8°C
- form
- clear liquid
- color
- Colorless to Almost colorless
- Water Solubility
- 62.2 mg/L · 62.2mg/L at 20℃
- Cosmetics Ingredients Functions
- FILM FORMING
- InChI
- 1S/C9H16O4/c1-8(2)9(10)13-7-6-12-5-4-11-3/h1,4-7H2,2-3H3
- InChIKey
- DAVVKEZTUOGEAK-UHFFFAOYSA-N
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (23.2%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P262, P264, P264+P265, P270, P271, P272, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P333+P317, P337+P317, P361+P364, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 56 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information
REACH registered substance: 2-(2-methoxyethoxy)ethyl methacrylate (EC: 256-190-2)
2-Propenoic acid, 2-methyl-, 2-(2-methoxyethoxy)ethyl ester: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesAcute Tox. 4 (23.2%)
Toxicology
Toxicity Summary
Based on available data, the CIR Expert Panel concluded that... Methoxydiglycol Methacrylate is safe as used in nail enhancement products when skin contact is avoided. Products containing these ingredients should be accompanied with directions to avoid skin contact, because of the sensitizing potential of Methacrylates.
Safe for use in cosmetics, with qualifications
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Methoxydiglycol Methacrylate
General Manufacturing Information2-Propenoic acid, 2-methyl-, 2-(2-methoxyethoxy)ethyl ester: ACTIVE
Applications
UsesTunable Cell-Adhesive Surfaces by Surface-Initiated Photoinduced Electron-Transfer-Reversible Addition-Fragmentation Chain-Transfer Polymerization.: This research utilizes Di(ethylene glycol) methyl ether methacrylate in the development of tunable cell-adhesive surfaces, crucial for biomedical applications such as tissue engineering and medical device manufacturing, due to its capacity for precise surface chemistry modifications (Kuzmyn et al., 2024). Temperature-Responsive Aldehyde Hydrogels with Injectable, Self-Healing, and Tunable Mechanical Properties.: This study demonstrates the use of Di(ethylene glycol) methyl ether methacrylate in creating temperature-responsive hydrogels, offering significant potential in medical device applications for minimally invasive surgical technologies and drug delivery systems (Zhao et al., 2022). Investigation of the Thermogelation of a Promising Biocompatible ABC Triblock Terpolymer and Its Comparison with Pluronic F127.: Highlighting its application in pharmaceutical formulations, this research explores the thermogelation properties of polymers including Di(ethylene glycol) methyl ether methacrylate, important for developing controlled drug release systems (Constantinou et al., 2022). Fabrication and Impact of Fouling-Reducing Temperature-Responsive POEGMA Coatings with Embedded CaCO(3) Nanoparticles on Different Cell Lines.: The study employs Di(ethylene glycol) methyl ether methacrylate in developing advanced coatings for biomedical devices, aiming to reduce fouling and enhance device longevity and functionality in clinical settings (Lishchynskyi et al., 2021). Nonionic UCST-LCST Diblock Copolymers with Tunable Thermoresponsiveness Synthesized via PhotoRAFT Polymerization.: This article presents the synthesis of unique block copolymers incorporating Di(ethylene glycol) methyl ether methacrylate, which are valuable in creating smart materials for dynamic biomedical and industrial applications (Xu & Abetz, 2021).
Suppliers81 total
Related reactions
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Compound notes
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