Myristamidopropyl Dimethylamine
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Basic information
- CAS
45267-19-4- Standard SMILES
CCCCCCCCCCCCCC(=O)NCCCN(C)C- InChIKey
IFYDWYVPVAMGRO-UHFFFAOYSA-N- Molecular formula
- C19H40N2O
- Average molar mass
- 312.5 g/mol
- Monoisotopic mass
- 312.3140639
Overview
The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Myristamidopropyl Dimethylamine...
Names & identifiers
- Preferred name
- Myristamidopropyl Dimethylamine
- IUPAC
- N-[3-(dimethylamino)propyl]tetradecanamide
- English name
- N-[3-(dimethylamino)propyl]myristamide
- Molecular formula
- C19H40N2O
- Molecular weight
- 312.53
Names & synonyms
45267-19-4AldoxMyristamidopropyl dimethylamineN-[3-(Dimethylamino)propyl]myristamideSchercodine MTetradecanamide, N-[3-(dimethylamino)propyl]-Dimethylaminopropyl myristamideM-dimethylamineYXS2X34V8WN-(3-(Dimethylamino)propyl)myristamideTetradecanamide, N-(3-(dimethylamino)propyl)-DTXSID2068470
Show more names
Aldox-d5Opti-free AldoxN,N-DimethylmyristamidopropylamineN-(3-(Dimethylamino)propyl)myristamid
SCHERCODINE M AMIDO-AMINERefChem:160405DTXCID4040395256-214-1N-(3-(Dimethylamino)propyl)tetradecanamideN-[3-(dimethylamino)propyl]tetradecanamideMFCD02029644Lexamine M 13
Database identifiers
- CAS
45267-19-4- PubChem CID
- 170759
- DTXSID
DTXSID2068470- UNII
- YXS2X34V8W
- EC Number
- 256-214-1
Properties
Computed structural propertiesFilling in
- XLogP
- 6.2
- Topological polar surface area
- 32.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 16
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 242
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Myristamidopropyl Dimethylamine) -> CIR (Cosmetic Ingredient Review)
Antistatic
Physical DescriptionCBI; Liquid
Physicochemical properties
- Melting point
- 49 · 49-51°C
- Boiling point
- 208 · 208-215 °C(Press: 1-2 Torr)
- Density
- 0.879 · 0.879
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 16.29 · 16.29±0.46(Predicted)
- color
- White to Off-White
- Cosmetics Ingredients Functions
- ANTISTATIC
- Cosmetic Ingredient Review (CIR)
- 3 · N-[3-(dimethylamino)propyl]myristamide (45267-19-4)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 0.8% (1 of 128) of reports.
Danger
H315 (98.4%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P280, P302+P352, P305+P354+P338, P317, P321, P332+P317, and P362+P364 (click each P-code to see the statement)
Aggregated GHS information provided per 128 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
Hazard information
Regulatory Information
Chemical: Tetradecanamide, N-[3-(dimethylamino)propyl]-
Tetradecanamide, N-[3-(dimethylamino)propyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Tetradecanamide, N-[3-(dimethylamino)propyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Other Safety InformationIMAP assessments - Fatty acid amido propyl dimethylamines: Human health tier II assessment
Hazard Classes and Categories
Skin Irrit. 2 (98.4%)
Skin corrosion - category 1
Toxicology
Toxicity Summary
The CIR Expert Panel concluded that the 24 fatty acid amidopropyl dimethylamines ingredients listed below are safe in cosmetics when they are formulated to be non-sensitizing, which may be based on a QRA...Myristamidopropyl Dimethylamine...
Safe for use in cosmetics, with qualifications
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationSubstances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection.
Uses & manufacturing
UsesCIR ingredient: Myristamidopropyl Dimethylamine
U.S. Production2023: 5,500,000 - <7,000,000 lb
Industry UsesIntermediate
Use ClassificationCosmetics -> Antistatic
General Manufacturing Information
All Other Basic Organic Chemical Manufacturing
Tetradecanamide, N-[3-(dimethylamino)propyl]-: ACTIVE
Applications
UsesMyristamidopropyl dimethylamine (MAPD), present as Aldox in Opti-Free Express Disinfecting Solution for contact lens care, was tested for its potential as a drug in treatment of Acanthamoeba keratitis. MAPD is an amidoamine compound that shows activity against Acanthamoeba as well as a variety of other causal agents of microbial keratitis.
Upstream & downstream products
Upstream raw materials
Related reactions
5 records
Compound notes
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