Glycyl-prolyl-arginine
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Basic information
- CAS
47295-77-2- Standard SMILES
NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C(N)N)C(=O)O- InChIKey
JYPCXBJRLBHWME-IUCAKERBSA-N- Molecular formula
- C13H24N6O4
- Average molar mass
- 328.37 g/mol
- Monoisotopic mass
- 328.18590327
Overview
Gly-Pro-Arg is a tripeptide.
Names & identifiers
- Preferred name
- Glycyl-prolyl-arginine
- IUPAC
- (2S)-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid
- English name
- H-Gly-Pro-Arg-OH
- Molecular formula
- C13H24N6O4
- Molecular weight
- 328.37
Names & synonyms
Glycyl-prolyl-arginine47295-77-2Gly-pro-argGlycylprolylarginineGlycyl-L-prolyl-L-arginineDTXSID00197085L-Arginine, N2-(1-glycyl-L-prolyl)-RefChem:143986DTXCID10119576G-P-R(2S)-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acidGPR
Show more names
H-Gly-Pro-Arg-OHL-Arginine, glycyl-L-prolyl-
Glycyl-L-prolyl-N~5~-(diaminomethylidene)-L-ornithineorb1981158SCHEMBL7853147CHEMBL3752079SCHEMBL29350916CHEBI:163949HY-P3528FG73425
Database identifiers
- CAS
47295-77-2- PubChem CID
- 170776
- DTXSID
DTXSID00197085- ChEMBL
CHEMBL3752079- ChEBI
CHEBI:163949- Nikkaji
- J378.769I
Properties
Computed structural propertiesFilling in
- XLogP
- -5.8
- Topological polar surface area
- 177 Ų
- Hydrogen bond donors
- 5
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 8
- Heavy atoms
- 23
- Formal charge
- 0
- Complexity
- 477
Chemistry & industry
Applications
UsesGPR is a three amino acid peptide. GPR can rescue cultured rat hippocampal neurons from Aβ-induced neuronal death by inhibiting caspase-3/p53 dependent apoptosis. GPR can be used for the research of Alzheimer's disease (AD).
Additional notes
DefinitionChEBI: Gly-Pro-Arg is an oligopeptide.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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