CAS 2461-15-6 2-Ethylhexyl glycidyl ether (HCID 17162)

Overview

2-ethylhexyl glycidyl ether is a clear colorless liquid. (NTP, 1992)

Names & identifiers

Preferred name: 2-Ethylhexyl glycidyl ether
IUPAC: 2-(2-ethylhexoxymethyl)oxirane
English name: 2-Ethylhexyl glycidyl ether
Molecular formula: C11H22O2
Molecular weight: 186.29

Names & synonyms

2-ETHYLHEXYL GLYCIDYL ETHER2461-15-6Glycidyl 2-ethylhexyl etherOxirane, [[(2-ethylhexyl)oxy]methyl]-(((2-Ethylhexyl)oxy)methyl)oxiraneOxirane, 2-[[(2-ethylhexyl)oxy]methyl]-2,3-Epoxypropyl-(2-ethylhexyl) etherOxirane, (((2-ethylhexyl)oxy)methyl)-((2-Ethylhexyl)methyl)oxirane[(2-Ethylhexyl)methyl]oxiraneCCRIS 2634DTXSID6025301

Show more names

EHGEglycidyl2-ethylhexyletheroctylglycinether2-ethvlhexvlglvcidvletherEthyl Hexyl Glycidyl EtherEthylhexyl glycidyl ether, 2-

3-(GLYCIDYLOXYMETHYL)HEPTANEEINECS 219-553-6Propane, 1,2-epoxy-3-((2-ethylhexyl)oxy)-NSC 252154BRN 1236919LU1UZ98B89Oxirane, 2-(((2-ethylhexyl)oxy)methyl)-[[(2-ethylhexyl)oxy]methyl]oxirane

Database identifiers

CAS: 2461-15-6
PubChem CID: 17162
DTXSID: DTXSID6025301
ChEMBL: CHEMBL1412431
UNII: LU1UZ98B89
EC Number: 219-553-6
Nikkaji: J216.100A

Properties

Computed structural properties

XLogP: 2.9
Topological polar surface area: 21.8 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 2
Rotatable bonds: 8
Heavy atoms: 13
Formal charge: 0
Complexity: 125

Experimental & physicochemical properties

Density0.893 at 68 °F (NTP, 1992) - Less dense than water; will float

Solubilityless than 1 mg/mL at 66 °F (NTP, 1992)

Flash Point206 °F (NTP, 1992)

Boiling Point244 to 248 °F at 20 mmHg (NTP, 1992)

Physical Description · 2 items

2-ethylhexyl glycidyl ether is a clear colorless liquid. (NTP, 1992)

Liquid

Physicochemical properties

Boiling point: 60 · 60-62 °C/0.3 mmHg (lit.)
Density: 0.891 g/mL · 0.891 g/mL at 25 °C (lit.)
vapor pressure: 29 Pa · 29Pa at 25℃
refractive index: 1.434 · 1.434
Flash point: 206 °F · 206°F
storage temp.: Store at room temperature
form: clear liquid
color: Colorless to Almost colorless
Specific Gravity: 0.91 · 0.910.891
Odor: Faint odor
Viscosity: 2.87 mm2/s · 2.87mm2/s
Water Solubility: 0.1 g/100 · <0.1 g/100 mL at 19 ºC
Stability: Stable. Combustible. Incompatible with strong oxidising agents, acids, bases.
InChI: 1S/C11H22O2/c1-3-5-6-10(4-2)7-12-8-11-9-13-11/h10-11H,3-9H2,1-2H3
InChIKey: BBBUAWSVILPJLL-UHFFFAOYSA-N
SMILES: CCCCC(CC)COCC1CO1
LogP: 3.83 · 3.83
CAS DataBase Reference: 2461 · 2461-15-6(CAS DataBase Reference)
FDA UNII: 1 UZ98B89 · LU1UZ98B89
NIST Chemistry Reference: Oxirane, [[(2-ethylhexyl)oxy]methyl]-(2461-15-6)
EPA Substance Registry System: 2 · 2-Ethylhexyl glycidyl ether (2461-15-6)
UNSPSC Code: 12162002 · 12162002
NACRES: 23 · NA.23
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 315 · H315-H317
Precautionary statements: 280 · P280-P302+P352
PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: Xi
Risk Statements: 36 · 36/37/38
Safety Statements: 26 · 26-37/39
WGK Germany: 2 · 2
RTECS: 3300000 · TZ3300000
TSCA: TSCA listed
HS Code: 29109000 · 29109000
Storage Class: 10 · 10 - Combustible liquids
Hazard Classifications: 2 Skin · Skin Irrit. 2Skin Sens. 1
Toxicity: 50 · rat,LD50,oral,7800mg/kg (7800mg/kg),"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2210, 1981.
REACH Registrations: Active

Safety & regulation

GHS classification

GHS Classification · 5 items

This chemical does not meet GHS hazard criteria for 0.5% (7 of 1458) of reports.

Warning

H315 (97.1%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 1458 reports by companies from 18 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

Regulatory Information · 5 items

Chemical: Oxirane, [[(2-ethylhexyl)oxy]methyl]-

Oxirane, 2-[[(2-ethylhexyl)oxy]methyl]- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2-[[(2-ethylhexyl)oxy]methyl]- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.

Status: Active Update: 15-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13238

Oxirane, [[(2-ethylhexyl)oxy]methyl]-: Does not have an individual approval but may be used under an appropriate group standard

Fire HazardsThis chemical is combustible. (NTP, 1992)

Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin and eyes.

Reactive GroupEthers

Reactivity Profile2-ETHYLHEXYL GLYCIDYL ETHER is incompatible with acids, bases and oxidizing agents. (NTP, 1992)

Air and Water ReactionsInsoluble in water.

Safety & protection

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)

First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Personal Protective Equipment (PPE) · 1 item

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Safety data

PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 2
tsca: TSCA listed
rtecs: TZ3300000
hs_code: 29109000
Toxicity: rat,LD50,oral,7800mg/kg (7800mg/kg),"Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2A, Pg. 2210, 1981.
risk_code: 36/37/38
Signal word: Warning
Symbol(GHS): GHS07
hazard_code: Xi
safety_code: 26-37/39
Storage Class: 10 - Combustible liquids
Hazard statements: H315-H317
REACH Registrations: Active
Hazard Classifications: Skin Irrit. 2Skin Sens. 1
Precautionary statements: P280-P302+P352

Chemistry & industry

Uses & manufacturing

U.S. Production2023: 700,000 - <850,000 lb

Consumer UsesPaint additives and coating additives not described by other categories

Industry UsesSolvent

General Manufacturing Information · 2 items

Paint and Coating Manufacturing

Oxirane, 2-[[(2-ethylhexyl)oxy]methyl]-: ACTIVE

Applications · 3 items

Uses2-Ethylhexyl glycidyl ether is a used as a commercial reactive diluent. It is also known to induce sister-chromatid exchanges in Chinese hamster cells.

UsesIt constitutes a reactive diluent and may be used as a relatively nonvolatile chloride-scavenging agent and stabilizer for vinyl resins and rubber.

General DescriptionClear colorless liquid.