pipes disodium salt
Basic information
- CAS
76836-02-7- Standard SMILES
O=S(=O)([O-])CCN1CCN(CCS(=O)(=O)[O-])CC1.[Na+].[Na+]- InChIKey
GMHSTJRPSVFLMT-UHFFFAOYSA-L- Molecular formula
- C8H16N2Na2O6S2
- Average molar mass
- 346.3 g/mol
- Monoisotopic mass
- 346.02451715
Overview
Disodium PIPES is an organic salt, being the disodium salt of 2,2'-piperazine-1,4-diylbisethanesulfonic acid (PIPES), a buffering agent. It has a role as a buffer. It contains a 2,2'-piperazine-1,4-diylbisethanesulfonate.
Names & identifiers
- Preferred name
- pipes disodium salt
- IUPAC
- disodium;2-[4-(2-sulfonatoethyl)piperazin-1-yl]ethanesulfonate
- English name
- Disodium piperazine-1,4-diethanesulphonate
- Molecular formula
- C8H16N2Na2O6S2
- Molecular weight
- 346.33
Names & synonyms
76836-02-7PIPES disodium salt1,4-Piperazinediethanesulfonic acid, disodium saltpipes disodiumDisodium piperazine-1,4-diethanesulphonateSODIUM PIPESATEO25162TU3UEINECS 278-562-31,4-Piperazinediethanesulfonic acid, sodium salt (1:2)DTXSID1072844PIPES DISODIUM SALT [MI]DISODIUM 1,4-PIPERAZINEBIS(ETHANESULFONATE)
Show more names
PIPES 2NAPIPES-NA2Piperazine-1isodiumPIPESPIPES NA2-SALTdisodium PIPESMAGNESIUM STANDPOTASSIUM STANDSTRONTIUM STAND
Piperazine1,4bis(2ethanesulfonic acid) disodium saltPiperazine, N,N'bis(2ethanesulfonic acid) disodium saltRefChem:863630DTXCID3047922Disodium piperazine1,4diethanesulphonate1,4Piperazinediethanesulfonic acid, disodium salt1,4Piperazinediethanesulfonic acid, sodium salt (1:2)1,4-Piperazinediethanesulfonic acid disodium salt
Properties
Computed structural properties
- Topological polar surface area
- 138 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 8
- Rotatable bonds
- 4
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 370
Experimental & physicochemical properties
Chemical ClassesOther Uses -> Biological Buffers
Physical DescriptionSolid; [Sigma-Aldrich MSDS]
Physicochemical properties
- Density
- 1.72 · 1.72[at 20℃]
- vapor pressure
- 0 Pa · 0Pa at 20℃
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- 2 O: · H2O: 0.5 g/mL, clear, colorless
- form
- Powder or Crystalline Powder
- color
- White
- PH Range
- 6.1 · 6.1 - 7.5
- pka
- 6.8 · 6.8(at 25℃)
- PH
- 6.1 · 6.1-7.5
- biological source
- synthetic
- Water Solubility
- 855 g/L · 855g/L at 19.8℃
- Merck
- 14 · 14,7479
- BRN
- 9453872 · 9453872
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 96% (48 of 50) of all reports.
Not Classified
Aggregated GHS information provided per 50 reports by companies from 3 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory Information
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
REACH registered substance: Disodium piperazine-1,4-diethanesulphonate (EC: 278-562-3)
1,4-Piperazinediethanesulfonic acid, disodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS]
Hazard Classes and CategoriesNot Classified
Safety data
- PPE
- Eyeshields, Gloves, type N95 (US)
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29335995
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-37/39-24/25
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Uses & manufacturing
UsesUsed as a biological buffer; [Merck Index]
General Manufacturing Information1,4-Piperazinediethanesulfonic acid, sodium salt (1:2): ACTIVE
Applications
UsesPIPES Disodium is the sodium salt form of PIPES and is a biological buffer often referred to as a “Good′s” buffer. The pKa of PIPES is 6.8 which makes it ideal for biological applications at physiological conditions. PIPES Disodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.PIPES Disodium can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for cell culture and diagnostic reagent production.
UsesBiological buffer.
Additional notes
DefinitionChEBI: An organic salt, being the disodium salt of 2,2'-piperazine-1,4-diylbisethanesulfonic acid (PIPES), a buffering agent.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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