N,N-Dimethyl-1-octadecanamine-N-oxide
Basic information
- CAS
2571-88-2- Standard SMILES
CCCCCCCCCCCCCCCCCC[N+](C)(C)[O-]- InChIKey
UTTVXKGNTWZECK-UHFFFAOYSA-N- Molecular formula
- C20H43NO
- Average molar mass
- 313.6 g/mol
- Monoisotopic mass
- 313.334465
Overview
On the basis of the available animal and clinical data presented in this report, the CIR Expert Panel concludes that Lauramine Oxide and Stearamine Oxide are safe as cosmetic ingredients for "rinse-off" products under present conditions of use. For use in "leave-on" products, the Expert Panel concludes that Lauramine Oxide should be limited to 3.7% and Stearamine Oxide to 5%.
Names & identifiers
- Preferred name
- N,N-Dimethyl-1-octadecanamine-N-oxide
- IUPAC
- N,N-dimethyloctadecan-1-amine oxide
- English name
- Dimethylstearylamine oxide
- Molecular formula
- C20H43NO
- Molecular weight
- 313.56
Names & synonyms
STEARAMINE OXIDE1-Octadecanamine, N,N-dimethyl-, N-oxideDimethylstearylamine oxideOctadecyldimethylamine oxideN,N-Dimethyloctadecylamine N-oxideSTEARYLDIMETHYLAMINE OXIDEUNII-241Y7MZO9UN,N-Dimethyl-1-octadecanamine-N-oxide241Y7MZO9UINCROMINE OXIDE SEINECS 219-919-5BARLOX 18S
Show more names
DONOAdMox 18Barlox 18AMMonyx SOConco XA 2SUnisafe A-SMAdMox SC 1885SchercaMox DMSstearamineoxide
DTXSID1051931RefChem:201918STEARAMINE OXIDE [INCI]DTXCID60304932571-88-2N,N-Dimethyloctadecylamine OxideN,N-dimethyloctadecan-1-amine oxideStearyl dimethylamine oxide
Database identifiers
- CAS
2571-88-2- PubChem CID
- 17388
Properties
Computed structural properties
- XLogP
- 8.5
- Topological polar surface area
- 18.1 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 17
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 216
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Stearamine Oxide) -> CIR (Cosmetic Ingredient Review)
Hair conditioning; Foam boosting; Antistatic; Hydrotrope; Surfactant; Cleansing
Physicochemical properties
- Melting point
- 132 · 132-151 °C
- vapor pressure
- 0 Pa · 0Pa at 25℃
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 4.79 · 4.79±0.40(Predicted)
- form
- paste
- Cosmetics Ingredients Functions
- ANTISTATICCLEANSINGSURFACTANT - HYDROTROPESURFACTANT - FOAM BOOSTINGHAIR CONDITIONINGSURFACTANT - CLEANSING
- LogP
- 6.145 · 6.145 (est)
- FDA UNII
- 241 Y7MZO9U · 241Y7MZO9U
- EPA Substance Registry System
- 1 · 1-Octadecanamine, N,N-dimethyl-, N-oxide (2571-88-2)
- Symbol(GHS)
- 7 · GHS07,GHS05,GHS09
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P273, P280, P301+P317, P302+P352, P305+P354+P338, P317, P321, P330, P332+P317, P362+P364, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 7 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
H400: Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]
Hazard information
Regulatory Information
Chemical: 1-Octadecanamine, N,N-dimethyl-, N-oxide
REACH registered substance: N,N-dimethyloctadecylamine N-oxide (EC: 219-919-5)
N,N-Dimethyl-1-octadecanamine-N-oxide: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and Categories
Acute Tox. 4 (100%)
Hazardous to the aquatic environment (Acute) - Category 1
Toxicology
Toxicity Summary
On the basis of the available animal and clinical data presented in this report, the CIR Expert Panel concludes that Lauramine Oxide and Stearamine Oxide are safe as cosmetic ingredients for "rinse-off" products under present conditions of use. For use in "leave-on" products, the Expert Panel concludes that Lauramine Oxide should be limited to 3.7% and Stearamine Oxide to 5%.
Safe for use in cosmetics, with qualifications
Safety data
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Stearamine Oxide
Household ProductsInformation on 1 consumer products that contain Stearamine Oxide in the following categories is provided:
Use ClassificationCosmetics -> Hair conditioning; Foam boosting; Antistatic; Hydrotrope; Surfactant; Cleansing
General Manufacturing Information1-Octadecanamine, N,N-dimethyl-, N-oxide: ACTIVE
Applications
UsesN,N-Dimethyloctadecylamine Oxide is a tertiary amine oxide used as an emulsifying agent. N,N-Dimethyloctadecylamine Oxide is also used to inhibit skin irritation in cosmetics.
UsesDimethylstearylamine oxide is a tertiary amine oxide used as an emulsifying agent. N,N-Dimethyloctadecylamine Oxide is also used to inhibit skin irritation in cosmetics.
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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