Victoria Blue B
Basic information
- CAS
2580-56-5- Standard SMILES
CN(C)c1ccc(C(=C2C=CC(=[NH+]c3ccccc3)c3ccccc32)c2ccc(N(C)C)cc2)cc1.[Cl-]- InChIKey
LLWJPGAKXJBKKA-UHFFFAOYSA-N- Molecular formula
- C33H32N3.Cl
- Average molar mass
- 506.1 g/mol
- Monoisotopic mass
- 505.2284757
Overview
Victoria blue B is an iminium salt composed of 4-{(4-anilinonaphthalen-1-yl)[4-(dimethylamino)phenyl]methylidene}-N,N-dimethylcyclohexa-2,5-dien-1-iminium and chloride ions in a 1:1 ratio. It binds to nucleic acids and can be used in standardised staining techniques suitable for automated cell-pattern recognition. It has a role as a fluorochrome and a histological dye. It is an iminium salt and an organic chloride salt. It contains a victoria blue B(1+).
Names & identifiers
- Preferred name
- Victoria Blue B
- IUPAC
- [4-[bis[4-(dimethylamino)phenyl]methylidene]naphthalen-1-ylidene]-phenylazanium chloride
- English name
- Basic Blue 26
- Molecular formula
- C33H32ClN3
- Molecular weight
- 506.09
Names & synonyms
Basic blue 26Victoria blue B2580-56-5Calcozine Blue BC.I. BASIC BLUE 26C.I. 44045CI 44045Z1V8UTB56CDTXSID0038889COVARIANE BLEU W 6129NSC-11245LOWACRYL BLUE 26
Show more names
[4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium chlorideHectoBlueBVictoriaBACI NO 44045BASIC BLUE BBVictoria blCorn blue BN
CHEBI:87651Methanaminium, N-(4-((4-(dimethylamino)phenyl)(4-(phenylamino)-1-naphthalenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-methyl-, chlorideMethanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chlorideRefChem:934023DTXCID8018889219-943-64-(alpha-(4-anilino-1-naphthyl)-p-dimethylamino)benzylidene-2,5-cyclohexadien-1-ylidenedimethyl ammonium chlorideN-(4-((4-(Dimethylamino)phenyl)(4-(phenylamino)-1-naphthalenyl)methylene)-2,5-cyclohexadien-1-ylidene)-N-methylmethanaminium, chloride
Database identifiers
Properties
Computed structural properties
- Topological polar surface area
- 20.5 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 5
- Heavy atoms
- 37
- Formal charge
- 0
- Complexity
- 769
Experimental & physicochemical properties
CosmeticsCosmetic colorant; Hair dyeing
Physical DescriptionLiquid
Physicochemical properties
- Melting point
- 206 °C · 206 °C (dec.)(lit.)
- Density
- 1.336 · 1.336[at 20℃]
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Powder
- Colour Index
- 44045 · 44045
- color
- Dark brown
- Water Solubility
- SOLUBLE IN HOT WATER
- BRN
- 4094258 · 4094258
- Stability
- Hygroscopic, Light Sensitive
- Cosmetics Ingredients Functions
- HAIR DYEINGCOLORANT
- InChI
- InChI=1S/C33H31N3.ClH/c1-35(2)27-18-14-24(15-19-27)33(25-16-20-28(21-17-25)36(3)4)31-22-23-32(30-13-9-8-12-29(30)31)34-26-10-6-5-7-11-26;/h5-23H,1-4H3;1H
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 10.2% (27 of 264) of reports.
Danger
H302 (84.8%): Harmful if swallowed [Warning Acute toxicity, oral]
P261, P264, P264+P265, P270, P272, P273, P280, P301+P317, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P330, P333+P317, P337+P317, P362+P364, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 264 reports by companies from 17 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Not Classified
Hazard information
Regulatory Information
Chemical: Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride
Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: [4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene]dimethylammonium chloride (EC: 219-943-6)
Substance: [4-[[4-anilino-1-naphthyl][4-(dimethylamino)phenyl]methylene]cyclohexa-2,5-dien-1-ylidene] dimethylammonium chloride (C.I. Basic Blue 26)
Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride: Does not have an individual approval but may be used under an appropriate group standard
Other Safety InformationIMAP assessments - Crystal violet and related dyes: Human health tier II assessment
Chemistry & industry
Uses & manufacturing
U.S. Production2023: <50,000 lb
Consumer UsesDye
Industry UsesDye
Use ClassificationCosmetics -> Cosmetic colorant; Hair dyeing
General Manufacturing Information
Synthetic Dye and Pigment Manufacturing
Methanaminium, N-[4-[[4-(dimethylamino)phenyl][4-(phenylamino)-1-naphthalenyl]methylene]-2,5-cyclohexadien-1-ylidene]-N-methyl-, chloride (1:1): ACTIVE
Applications
UsesBasic Blue 26 used in the quantitative determination of phospholipids and as a nuclear stain in cytology/histochemical applications.
UsesVictoria Blue B is used as a nuclear stain in cytology/histochemical applications. Victoria Blue B may be used in the quantitative determination of phospholipids.
Preparation methods
Preparation(a) 4-(Dichloro(4-(diethylamino)phenyl)methyl)-N,N-diethylbenzenamine and Naphthalen-1-amine condensation; (b) Bis (4 – (dimethylamino) phenyl) methanol and Naphthalen-1-amine condensation, the product into N-and the nitro derivatives, and then oxidation, remove the nitro.
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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