Etamsylate

HCID 17506CAS 2624-44-4

Basic information

Standard SMILES
CCNCC.O=S(=O)(O)c1cc(O)ccc1O
InChIKey
HBGOLJKPSFNJSD-UHFFFAOYSA-N
Molecular formula
C10H17NO5S
Average molar mass
263.31 g/mol
Monoisotopic mass
263.08274382

Names & identifiers

Preferred name
Etamsylate
IUPAC
2,5-dihydroxybenzenesulfonic acid;N-ethylethanamine
English name
Etamsylate
Molecular formula
C10H17NO5S
Molecular weight
263.31

Names & synonyms

EtamsylateETHAMSYLATE2624-44-4CyclonamineDicyneneEtamsilatoEtamsylatumEtamsilateMD 141E 141Diethylamine dobesilateDTXSID4045559
Show more names
Phenolsulfonatee141md141eselinHeMsylK-StatSylatealtodoraglumin
24YL531VOHMD-141DTXCID2025559E-141Dicynene 1000RefChem:55154B02BX012,5-dihydroxybenzene-1-sulfonic acid; diethylamine

Database identifiers

CAS
2624-44-4
PubChem CID
17506
DTXSID
DTXSID4045559
ChEMBL
CHEMBL1514715
ChEBI
CHEBI:31563
UNII
24YL531VOH
EC Number
220-090-7

Properties

Computed structural properties

Topological polar surface area
115 Ų
Hydrogen bond donors
4
Hydrogen bond acceptors
6
Rotatable bonds
3
Heavy atoms
17

Physicochemical properties

Melting point
125 ° · 125°
Density
1.3441 · 1.3441 (rough estimate)
refractive index
1.506 · 1.5060 (estimate)
storage temp.
Keep in dark place,Inert atmosphere,Room temperature
solubility
Very soluble in water, freely soluble in methanol, soluble in anhydrous ethanol, practically insoluble in methylene chloride.
form
Solid

Safety & regulation

GHS classification

GHS Classification · 6 items

This chemical does not meet GHS hazard criteria for 12.2% (5 of 41) of reports.

Warning

H319 (85.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

P264+P265, P280, P305+P351+P338, and P337+P317 (click each P-code to see the statement)

Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory.;Reported as not meeting GHS hazard criteria per 5 of 41 reports by companies.;There are 2 notifications provided by 36 of 41 reports by companies with hazard statement code(s).;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory InformationChemical: Benzenesulfonic acid, 2,5-dihydroxy-, compound with N-ethylethanamine (1:1)
Other Safety InformationEvaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia
Hazard Classes and CategoriesEye Irrit. 2 (85.4%)

Regulatory information

Regulatory InformationChemical: Benzenesulfonic acid, 2,5-dihydroxy-, compound with N-ethylethanamine (1:1)

Safety data

wgk
WGK 3
tsca
TSCA listed
rtecs
DB6145000
hs_code
2921.19.6190
Toxicity
LD50 i.v. in mice, rats: 800, 1350 mg/kg (Esteve)
Signal word
Warning

Chemistry & industry

Pharmacology

ATC Code · 3 items

B02BX01

B - Blood and blood forming organs;B02 - Antihemorrhagics;B02B - Vitamin k and other hemostatics;B02BX - Other systemic hemostatics;B02BX01 - Etamsylate

QB - Blood and blood forming organs;QB02 - Antihemorrhagics;QB02B - Vitamin k and other hemostatics;QB02BX - Other systemic hemostatics;QB02BX01 - Etamsylate

MeSH Pharmacological Classification · 1 item

Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.

Uses & manufacturing

General Manufacturing InformationBenzenesulfonic acid, 2,5-dihydroxy-, compd. with N-ethylethanamine (1:1): INACTIVE

Applications

UsesHaemostatic / Anti Coagulant

UsesHemostatic;prostaglandin synthesis inhibitor

Upstream & downstream products

Suppliers50 total

上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
Baoji Guokang Healthchem co.,ltd+8615604608665 15604608665 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Jai Radhe Sales+(91)-(79)-26431096/65255722 · [email protected]

Additional notes

DefinitionChEBI: Etamsylate is a sulfonic acid derivative and an organosulfur compound.

Related reactions

3 records

Linked notes

Loading…