Basic information
- CAS
51486-77-2- Standard SMILES
O=C(O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1- InChIKey
IYZPSKQQQWDBBG-ZZADNGCVSA-N- Molecular formula
- C84H121N21O22
- Average molar mass
- 1,777 g/mol
- Monoisotopic mass
- 1,775.89950457
Overview
Vezocolmitide is under investigation in clinical trial NCT06178679 (Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease (DED)).
Names & identifiers
- Preferred name
- Vezocolmitide
- IUPAC
- 2-[[(2S)-1-[(2S)-1-[2-[[(2S)-1-[(2S)-1-[2-[[(2S)-1-[(2S)-1-[2-[[(2S)-1-[(2S)-1-[2-[[(2S)-1-[(2S)-1-[2-[[(2S)-1-[(2S)-1-[2-[[(2S)-1-[(2S)-pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]acetic acid
- English name
- Glycine, L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolyl-
- Molecular formula
- C84H121N21O22
- Molecular weight
- 1776.99
Names & synonyms
51486-77-2VezocolmitideVezocolmitide (USAN/INN)orb2942732SCHEMBL29816377EX-A14007TP3144D13326Glycine, L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolylglycyl-L-prolyl-L-prolyl-
Database identifiers
- CAS
51486-77-2- PubChem CID
- 175772080
- ChEMBL
CHEMBL6068188
Properties
Computed structural properties
- XLogP
- -6.3
- Topological polar surface area
- 517 Ų
- Hydrogen bond donors
- 9
- Hydrogen bond acceptors
- 23
- Rotatable bonds
- 28
- Heavy atoms
- 127
- Formal charge
- 0
- Complexity
- 4,320
Physicochemical properties
- Melting point
- 5 °C · <5 °C
- Density
- 1.43 · 1.430±0.06 g/cm3(Predicted)
- pka
- 3.67 · 3.67±0.10(Predicted)
Chemistry & industry
Applications
UsesVezocolmitide is a collagen mimetic peptide and is the component of ST-100. Vezocolmitide can be used for research of dry eye disease (DED)[1][2].
Suppliers4 total
杭州思诺达医药科技有限责任公司0571-87213919 17306812703 · [email protected]
江西辐氨生物技术有限公司15002819872 · [email protected]
杭州肽佳生物科技有限公司0571-87213919 15967184799 · [email protected]
江西研肽生物医药科技有限公司13758194781; 13758194781 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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