Basic information
- CAS
98717-15-8- Standard SMILES
CCCN1CCCC[C@H]1C(=O)Nc1c(C)cccc1C.Cl- InChIKey
NDNSIBYYUOEUSV-RSAXXLAASA-N- Molecular formula
- C17H27ClN2O
- Average molar mass
- 310.9 g/mol
- Monoisotopic mass
- 310.1811912
Names & identifiers
- Preferred name
- Ropivacaine Hydrochloride
- IUPAC
- (2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide;hydrochloride
- English name
- Ropivacaine hydrochloride
- Molecular formula
- C17H26N2O.ClH
- Molecular weight
- 310.86
Names & synonyms
Ropivacaine hydrochlorideROPIVACAINE HCl98717-15-8Ropivacaine monohydrochlorideDTXSID204837935504LBE2TDTXCID2028353ROPIVACAINE HYDROCHLORIDE [MI]ROPIVACAINE HYDROCHLORIDE [MART.]ROPIVACAINE HYDROCHLORIDE ANHYDROUSROPIVACAINE HYDROCHLORIDE [WHO-DD]2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-, monohydrochloride, (S)-
Show more names
S-ROPIVACAINE HCLRopivacaine mesilateRopivacaine hydrochlROPIVCACAINE HYDROCHLORIDERopivacaine HCl (anhydrous)(S)-ROPIVACAINE HYDROCHLORIDE
(S)-(-)-1-PROPYL-2',6'-PIPECOLOXYLIDINE HYDROCHLORIDE(S)-(-)-1-PROPYLPIPERIDINE-2-CARBOXYLIC ACID (2,6-DIMETHYLPHENYL)AMIDE HYDROCHLORIDEROPIVACAINE HYDROCHLORIDE (MART.)ROPIVACAINE HYDROCHLORIDE [VANDF]ROPIVACAINE HYDROCHLORIDE [ORANGE BOOK]ROPIVACAINE HYDROCHLORIDE (USP MONOGRAPH)ROPIVACAINE HYDROCHLORIDE [USP MONOGRAPH]ROPIVACAINE HYDROCHLORIDE MONOHYDRATE [MI]
Database identifiers
- CAS
98717-15-8
Properties
Computed structural properties
- Topological polar surface area
- 32.3 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 4
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 308
Physicochemical properties
- Melting point
- 260 · 260-262°
- alpha
- 25 · D25 -6.6° (c = 2 in water)
- storage temp.
- -20 °C · Store at -20°C
- form
- Solid
- color
- White to off-white
- Water Solubility
- 10.1 mg/mL · ≥ 10.1mg/mL in Water
- Major Application
- pharmaceutical small molecule
- InChI
- InChI=1S/C17H26N2O.ClH/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H
- InChIKey
- NDNSIBYYUOEUSV-UHFFFAOYSA-N
- SMILES
- N1(CCC)CCCCC1C(NC1=C(C)C=CC=C1C)=O.[H]Cl
- CAS DataBase Reference
- 98717 · 98717-15-8(CAS DataBase Reference)
- FDA UNII
- 35504 LBE2T · 35504LBE2T
- UNSPSC Code
- 41116107 · 41116107
- NACRES
- 24 · NA.24
- Symbol(GHS)
- 5 · GHS05
- Signal word
- Warning
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H332 (100%): Harmful if inhaled [Warning Acute toxicity, inhalation]；H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H412 (100%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Safety data
- wgk
- WGK 3
- Signal word
- Warning
- Symbol(GHS)
- GHS05
- Storage Class
- 13 - Non Combustible Solids
- Hazard statements
- H315-H302-H335-H332-H319-H412
- Hazard Classifications
- Eye Dam. 1
- Precautionary statements
- P273-P501-P261-P271-P304+P340-P312-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501
Chemistry & industry
Pharmacology
FDA Pharmacological Classification
ROPIVACAINE HYDROCHLORIDE
Amide Local Anesthetic [EPC]; Amides [CS]; Local Anesthesia [PE]
MeSH Pharmacological Classification
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
Applications
Usesanesthetic
Uses2-Piperidinecarboxamide hydrochloride is a useful research chemical compound.
Upstream & downstream products
Downstream products
Suppliers101 total
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
河南赢创生物科技有限公司16650615803 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
Related reactions
1 records
Compound notes
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