HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-p-cresol
3-amino-p-cresol · Phenol, 3-amino-4-methyl- · m-Amino-p-cresol · p-Cresol, 3-amino- · 5-Hydroxy-o-toluidine · 3-AMINO-4-METHYLPHENOL · 3-azanyl-4-methyl-phenol · 2-AMINO-4-HYDROXYTOLUENE
Identifiers & Physical Properties
| CAS No. | 2836-00-2 |
|---|---|
| Molecular formula | C7H9NO |
| Average molar mass | 123.15 g/mol |
| Monoisotopic mass | 123.06841391 g/mol |
| SMILES | Cc1ccc(O)cc1N |
| InChIKey | NUNAWQZKZVVELQ-UHFFFAOYSA-N |
| PubChem CID | 17820 |
| EC No. | 220-622-8 |
| DTXSID | DTXSID3074860 |
Chemical & Physical Properties
| XLogP | 0.5 |
|---|---|
| Topological polar surface area | 46.3 |
| Hydrogen bond donors | 2 |
| Hydrogen bond acceptors | 2 |
| Rotatable bonds | 0 |
| Heavy atoms | 9 |
| Formal charge | 0 |
| Complexity | 94.9 |
| Chemical classes | Nitrogen Compounds -> Amino Phenols |
| Boiling point | Sublimes (NTP, 1992)229.26°C (rough estimate) |
| Melting point | 313 to 315 °F (NTP, 1992)156-157°C |
| Physical Description | Crystals. (NTP, 1992)Solid[CAMEO] |
| Density | 1.0877 (rough estimate) |
| Refractive index | 1.5706 (estimate) |
| Storage conditions | Keep in dark place,Inert atmosphere,Room temperature |
| Physical state | powder to crystal |
| pKa (acidity coefficient) | 10.32±0.18(Predicted) |
| Color | Light yellow to Brown to Dark green |
| CAS DataBase Reference | 2836-00-2(CAS DataBase Reference) |
| EPA Substance Registry System | 3-Amino-4-methylphenol (2836-00-2) |
| GHS pictogram | GHS07 |
| Signal word | Warning |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P271-P261-P280 |
| Hazard symbols | Xi |
| Hazard Note | Irritant |
| Customs code | 2922290090 |
Safety & Regulations
| GHS classification | WarningH315 (97%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 33 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| DOT label | Poison |
| Fire hazards | Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992) |
| Health hazards | SYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes and mucous membranes. |
| Hazards summary | May cause skin, eye, and mucous membrane irritation[CAMEO] A local irritant[NTP] An irritant[Apollo Scientific MSDS] See Cresol, all isomers and o-Toluidine. |
| Reactive group | Phenols and Cresols |
| Reactivity Profile | 3-AMINO-4-METHYLPHENOL reacts with strong oxidizing agents. (NTP, 1992) |
| Air and Water Reactions | It may be sensitive to prolonged exposure to air. |
| Hazard Classes and Categories | Skin Irrit. 2 (97%) |
| Fire fighting | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| First aid | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| Nonfire spill response | SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| Isolation and Evacuation | Excerpt from ERG Guide 152 [Substances - Toxic (Combustible)]: |
| Personal Protective Equipment (PPE) | MINIMUM PROTECTIVE CLOTHING: If Tyvek protective clothing is not worn during the handling of this chemical, wear disposable Tyvek sleeves taped to your gloves. |
| Customs code | 2922290090 |
| Signal word | Warning |
| GHS pictogram | GHS07 |
| Hazard symbols | Xi |
| hazard_note | Irritant |
| GHS hazard statements | H315-H319-H335 |
| GHS precautionary statements | P271-P261-P280 |
Applications & Uses
General Description
Crystals.