3-Amino-p-cresol (HCID 17820)

Overview

Crystals. (NTP, 1992)

Names & identifiers

Preferred name: 3-Amino-p-cresol
IUPAC: 3-amino-4-methylphenol
English name: 3-Amino-4-methylphenol
Molecular formula: C7H9NO
Molecular weight: 123.15

Names & synonyms

3-AMINO-4-METHYLPHENOL2836-00-22-Amino-4-hydroxytoluenePhenol, 3-amino-4-methyl-3-Amino-p-cresolp-Cresol, 3-amino-EINECS 220-622-8DTXSID30748603A4MP5Hydroxyotoluidine3Amino4methylphenol2Amino4hydroxytoluene

Show more names

m-Amino-p-cresol3-azanyl-4-methyl-phenol3-Amino-4-Methylphenol 98%

Phenol, 3amino4methylRefChem:4976865-HYDROXY-O-TOLUIDINEDTXCID0037811220-622-83-Amino-4-methyl-phenolMFCD000750835-hydroxy-2-methylaniline

Database identifiers

CAS: 2836-00-2
PubChem CID: 17820
DTXSID: DTXSID3074860
EC Number: 220-622-8
Nikkaji: J13.737E

Properties

Computed structural properties

XLogP: 0.5
Topological polar surface area: 46.3 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 2
Rotatable bonds: 0
Heavy atoms: 9
Formal charge: 0
Complexity: 94.9

Experimental & physicochemical properties

Chemical ClassesNitrogen Compounds -> Amino Phenols

Boiling PointSublimes (NTP, 1992)

Melting Point313 to 315 °F (NTP, 1992)

Physical Description · 2 items

Crystals. (NTP, 1992)

Solid; [CAMEO]

Physicochemical properties

Melting point: 156 · 156-157°C
Boiling point: 229.26 °C · 229.26°C (rough estimate)
Density: 1.0877 · 1.0877 (rough estimate)
refractive index: 1.5706 · 1.5706 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder to crystal
pka: 10.32 · 10.32±0.18(Predicted)
color: Light yellow to Brown to Dark green
CAS DataBase Reference: 2836 · 2836-00-2(CAS DataBase Reference)
EPA Substance Registry System: 3 · 3-Amino-4-methylphenol (2836-00-2)
Symbol(GHS): 7 · GHS07
Signal word: Warning
Hazard statements: 315 · H315-H319-H335
Precautionary statements: 271 · P271-P261-P280
Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2922290090 · 2922290090

Safety & regulation

GHS classification

GHS Classification · 4 items

Warning

H315 (97%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 33 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Hazard information

DOT LabelPoison

Fire HazardsFlash point data for this chemical are not available. It is probably combustible. (NTP, 1992)

Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes and mucous membranes.

Hazards SummaryMay cause skin, eye, and mucous membrane irritation; [CAMEO] A local irritant; [NTP] An irritant; [Apollo Scientific MSDS] See Cresol, all isomers and o-Toluidine.

Reactive GroupPhenols and Cresols

Reactivity Profile3-AMINO-4-METHYLPHENOL reacts with strong oxidizing agents. (NTP, 1992)

Safety & protection

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 152 [Substances - Toxic (Combustible)]:

Personal Protective Equipment (PPE)MINIMUM PROTECTIVE CLOTHING: If Tyvek protective clothing is not worn during the handling of this chemical, wear disposable Tyvek sleeves taped to your gloves.