2-(7-(3,3-Dimethyl-1-octadecylindolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-octadecyl-3H-indol-1-ium iodide
Basic information
- CAS
100068-60-8- Standard SMILES
CCCCCCCCCCCCCCCCCCN1C(=C/C=C/C=C/C=C/C2=[N+](CCCCCCCCCCCCCCCCCC)c3ccccc3C2(C)C)C(C)(C)c2ccccc21.[I-]- InChIKey
JLIOTPLALDYAEH-UHFFFAOYSA-M- Molecular formula
- C63H101IN2
- Average molar mass
- 1,013.4 g/mol
- Monoisotopic mass
- 1,012.70095
Names & identifiers
- Preferred name
- 2-(7-(3,3-Dimethyl-1-octadecylindolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-octadecyl-3H-indol-1-ium iodide
- IUPAC
- 2-[(2E,4E,6E)-7-(3,3-dimethyl-1-octadecylindol-1-ium-2-yl)hepta-2,4,6-trienylidene]-3,3-dimethyl-1-octadecylindole iodide
- English name
- DiR'DiIC18(7) [1,1'-Dioctadecyl-3,3,3',3'-tetraMethylindotricarbocyanine iodide
- Molecular formula
- C63H101IN2
- Molecular weight
- 1013.42
Names & synonyms
100068-60-82-(7-(3,3-Dimethyl-1-octadecylindolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-octadecyl-3H-indol-1-ium iodide2-((1E,3E,5E)-7-((E)-3,3-dimethyl-1-octadecylindolin-2-ylidene)hepta-1,3,5-trien-1-yl)-3,3-dimethyl-1-octadecyl-3H-indol-1-ium iodideDIRCy7 DiC18DiR' [DiIC18(7)]1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOTRICARBOCYANINE IODIDE1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOTRICARBOCYANINE IODIDEDiR/Cy7/18lipo Cy7(C18)2DiR'' [DiIC18(7)lipo Cy7-di C18
Show more names
DiR Membrane Staining Kit
Database identifiers
- CAS
100068-60-8
Properties
Computed structural properties
- Topological polar surface area
- 6.3 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 38
- Heavy atoms
- 66
- Formal charge
- 0
- Complexity
- 1,260
Physicochemical properties
- storage temp.
- -20 °C · Amber Vial, -20°C Freezer, Under inert atmosphere
- solubility
- Methanol (Slightly, Heated), Water (Very Slightly, Heated, Sonicated)
- form
- Solid
- color
- Dark Blue to Very Dark Purple
- Appearance
- Blue paint solid
- ex/em
- 750 · 750/784 nm (Ethanol)
- ε(extinction coefficient)
- 252000 L⋅mol−1⋅cm−1 · 252000 L⋅mol−1⋅cm−1
- Stability
- Light Sensitive
- InChIKey
- JLIOTPLALDYAEH-UHFFFAOYSA-M
- SMILES
- C(N1C(C(C)(C)C2=CC=CC=C12)=CC=CC=CC=CC1C(C2=CC=CC=C2[N+]=1CCCCCCCCCCCCCCCCCC)(C)C)CCCCCCCCCCCCCCCCC.[I-]
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, and P362+P364 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H315-H319-H335
- Precautionary statements
- P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501
Chemistry & industry
Applications
DescriptionDiR is a near-infrared fluorescent carbocyanine dye for cell membrane labeling in vivo and in vitro. DiR diffuses laterally to stain the entire cell, allowing it to be used as an anterograde and retrograde tracer of neurons. In intact tissue, the dye does not transfer from labeled to unlabeled cells, but some transfer may occur when the membrane is disrupted, for example, after sectioning. The dye is weakly fluorescent until incorporated into membranes. DiR can be used with other tracers in multi-color studies, such as DiI or DiO and for NIR imaging.
UsesFluorescent lipophilic tracer
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…