31621-87-1*CCOCC(=O)O*31621-87-1DescriptionPolydioxanone, also known as poly-p-dioxanone, is a colorless, crystalline, biodegradable synthetic polymer. Polydioxanone is used in numerous medical applications, e.g., biodegradable sutures and implants, for its excellent biocompatibility and appropriate degradation time[1]. As a biodegradable suturesa, it has greater initial tensile strength than polyglycolic acid and polyglactin 910 but has the poorest knot security of the synthetic absorbable suture. The material is suitable and advantageous in cardiovascular operations where autologous tissue is handled. Polydioxanone clips could used in ligation of branches of the autologous vein grafts in femoropopliteal bypass and aortocoronary bypass. The polydioxanone clips did not slip when burst-tested in vitro[2].
UsesMedical device
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DefinitionPolydioxanone is a macromolecule composed of repeating 2-hydroxyethoxyacetyl units, obtained via ring-opening polymerisation of p-dioxanone.