CAS 2855-19-8 1,2-Epoxydodecane (HCID 17858)

Overview

1,2-epoxydodecane is a clear colorless liquid. (NTP, 1992)

Names & identifiers

Preferred name: 1,2-Epoxydodecane
IUPAC: 2-decyloxirane
English name: 1,2-Epoxydodecane
Molecular formula: C12H24O
Molecular weight: 184.32

Names & synonyms

1,2-EPOXYDODECANE2855-19-81-Dodecene oxideOxirane, decyl-Decyloxirane1,2-Dodecene oxideDecyl oxiraneDodecene epoxideDodecane, 1,2-epoxy-Nedox 12001,2-Dodecane oxide1,2-Epoxy-n-dodecene

Show more names

2-DecyloxiraneEDD1-DODECENE EPOXIDEDD5EDD1hHYDnedox1200Vikolox-12

1,2-Epoxy-N-dodecane1,2-Epoxydodekanalpha-Dodecene oxideNSC 6785CCRIS 2616DTXSID9025243HSDB 5538EINECS 220-667-3

Database identifiers

CAS: 2855-19-8
PubChem CID: 17858
DTXSID: DTXSID9025243
ChEMBL: CHEMBL3183029
UNII: 736974CF3U
EC Number: 220-667-3
Nikkaji: J13.742A

Properties

Computed structural properties

XLogP: 5.2
Topological polar surface area: 12.5 Å²
Hydrogen bond donors: 0
Hydrogen bond acceptors: 1
Rotatable bonds: 9
Heavy atoms: 13
Formal charge: 0
Complexity: 112

Experimental & physicochemical properties

PolymersPlastics & Rubber -> Epoxides

SpringerMaterials PropertiesOptical coefficient

Density0.844 (NTP, 1992) - Less dense than water; will float

Solubilityless than 1 mg/mL at 73 °F (NTP, 1992)

Flash Point · 2 items

112 °F (NTP, 1992)

44 °C

Boiling Point255 to 257 °F at 15 mmHg (NTP, 1992)

Physicochemical properties

Boiling point: 124 · 124-125 °C/15 mmHg (lit.)
Density: 0.844 g/mL · 0.844 g/mL at 25 °C (lit.)
vapor pressure: 2 mmHg · 2 mmHg ( 100 °C)
refractive index: 1.435 · 1.435-1.437
Flash point: 105 °C · 105 °C
storage temp.: 2 · 2-8°C
form: clear liquid
Specific Gravity: 0.844 · 0.844
color: Colorless to Almost colorless
biological source: goat
Water Solubility: Not miscible in water.
BRN: 105569 · 105569
InChI: 1S/C12H24O/c1-2-3-4-5-6-7-8-9-10-12-11-13-12/h12H,2-11H2,1H3
InChIKey: MPGABYXKKCLIRW-UHFFFAOYSA-N
SMILES: CCCCCCCCCCC1CO1
LogP: 5.9 at · 5.9 at 20℃
CAS DataBase Reference: 2855 · 2855-19-8(CAS DataBase Reference)
EWG's Food Scores: 1 · 1
FDA UNII: 736974 CF3U · 736974CF3U
NIST Chemistry Reference: Oxirane, decyl-(2855-19-8)
EPA Substance Registry System: 1 · 1,2-Epoxydodecane (2855-19-8)
UNSPSC Code: 12352203 · 12352203
NACRES: 43 · NA.43
Symbol(GHS): 7 · GHS07,GHS09
Signal word: Warning
Hazard statements: 315 · H315-H410
Precautionary statements: 264 · P264-P273-P280-P302+P352-P332+P313-P362+P364
PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes: Xi
Risk Statements: 36 · 36/37/38
Safety Statements: 26 · 26-36-37/39
WGK Germany: 1 · 1
RTECS: 2450000 · JR2450000
F: 10 · 10-23
TSCA: TSCA listed
HS Code: 29109000 · 29109000
Storage Class: 10 · 10 - Combustible liquids
Hazard Classifications: 1 Aquatic · Aquatic Acute 1Aquatic Chronic 1Skin Irrit. 2
Hazardous Substances Data: 2855 · 2855-19-8(Hazardous Substances Data)
REACH Registrations: Active

Safety & regulation

GHS classification

GHS Classification · 6 items

Warning

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 174 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Warning

H315: Causes skin irritation [Warning Skin corrosion/irritation]

Hazard information

Regulatory Information · 4 items

Chemical: Oxirane, decyl-

Oxirane, 2-decyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Oxirane, 2-decyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 15-03-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/12323

1,2-Epoxydodecane: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationIMAP assessments - Long-chain alkyl oxiranes: Human health tier II assessment

DOT LabelFlammable Liquid

Fire HazardsThis chemical is combustible. (NTP, 1992)

Health HazardsSYMPTOMS: Symptoms of exposure to this compound may include irritation of the skin, eyes, mucous membranes and upper respiratory tract.

Hazards SummaryA tumorigen; [RTECS] A skin, eye, mucous membrane, and upper respiratory tract irritant; [CAMEO] An irritant; [MSDSonline]

Safety & protection

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used. (NTP, 1992)

First Aid · 1 item

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 item

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]:

Personal Protective Equipment (PPE) · 1 item

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Toxicology

Non-Human Toxicity ExcerptsCARCINOGENIC POTENTIAL OF 1,2-EPOXYDODECANE RESULTED IN 0/30 MICE AFTER DERMAL APPLICATION TO MICE. /FROM TABLE/

Safety data

F: 10-23
PPE: Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk: 1
tsca: TSCA listed
rtecs: JR2450000
hs_code: 29109000
risk_code: 36/37/38
Signal word: Warning
Symbol(GHS): GHS07,GHS09
hazard_code: Xi
safety_code: 26-36-37/39
Storage Class: 10 - Combustible liquids
Hazard statements: H315-H410
REACH Registrations: Active
Hazard Classifications: Aquatic Acute 1Aquatic Chronic 1Skin Irrit. 2
Precautionary statements: P264-P273-P280-P302+P352-P332+P313-P362+P364
Hazardous Substances Data: 2855-19-8(Hazardous Substances Data)

Chemistry & industry

Uses & manufacturing

Uses · 2 items

Used as a secondary heat stabilizer for polymers; No known commercial production in the US; [HSDB]

SECONDARY HEAT STABILIZER FOR POLYMERS

U.S. Exports · 2 items

(1979) No Data

(1981) No Data

U.S. Imports · 2 items

(1979) No Data

(1981) No Data

U.S. Production · 3 items

2023: 34,534 lb

(1979) NO EVIDENCE OF COMMERCIAL PRODN IN U.S.

(1981) NO EVIDENCE OF COMMERCIAL PRODN IN U.S.

Consumer UsesHeat transferring agent

Industry UsesHeat transferring agent

Applications · 2 items

UsesIn the production of epoxy resins, 1,2-Epoxydodecane is used as a reactive diluent and cross-linking agent which can help to improve the performance and versatility of these industrial materials. In the production of emulsions, foams, and dispersants, 1,2-Epoxydodecane can be used as a surfactant. In pharmaceutical industry, 1,2-Epoxydodecane can be used as a solvent in the production of certain pharmaceuticals, like pyrazolones. In the synthesis of hydroxyurea, 1,2-epoxydodecane is used as an intermediate in the production of a key starting material.

General DescriptionClear colorless liquid.