Gly-PEG3-endo-BCN
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Basic information
- CAS
2354291-37-3- Standard SMILES
NCC(=O)NCCCOCCOCCOCCCNC(=O)OC[C@@H]1C2CCC#CCC[C@@H]21- InChIKey
MZZHRBCWKALCAE-YSTUSHMSSA-N- Molecular formula
- C23H39N3O6
- Average molar mass
- 453.57 g/mol
Names & identifiers
- Preferred name
- Gly-PEG3-endo-BCN
- English name
- Gly-PEG3-endo-BCN
- Molecular formula
- C23H39N3O6
- Molecular weight
- 453.57
Names & synonyms
Gly-PEG3-endo-BCNGly-PEG3-endo-BCN, TFA salt6,9,12-Trioxa-2,16-diazaoctadecanoic acid, 18-amino-17-oxo-, (1α,8α,9β)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester
Database identifiers
- CAS
2354291-37-3
Properties
Physicochemical properties
- Boiling point
- 656.9 · 656.9±55.0 °C(Predicted)
- Density
- 1.16 · 1.16±0.1 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 12.48 · 12.48±0.46(Predicted)
Chemistry & industry
Applications
DescriptionGly-PEG3-endo-BCN is a click chemistry reagent. The hydrophilic PEG spacer increases solubility in aqueous media.
UsesGly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Related reactions
0 records
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Compound notes
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