3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine
Basic information
- CAS
131474-72-1- Standard SMILES
CC(C)[Si]1(C(C)C)OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(NC(=O)COc5ccccc5)nc43)[C@H](O)[C@@H]2O[Si](C(C)C)(C(C)C)O1- InChIKey
RRWDFNRJFKNJIJ-QTWDEJAXSA-N- Molecular formula
- C30H45N5O8Si2
- Average molar mass
- 659.88 g/mol
Names & identifiers
- Preferred name
- 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine
- English name
- 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)uridine
- Molecular formula
- C30H45N5O8Si2
- Molecular weight
- 659.88
Names & synonyms
3',5'-TIPS-PAc-rG3',5'-TIPS-N-PAC-GN2-Pac-3',5'-TIPDS-Gr3',5'-TIPS-N-PAc-Guanosine3’,5’-TIPS-N-PAc-GuanosineN2-Pac-3',5'-O-TIPDSguanosineN2-Pac-3’,5’-O-TIPDS guanosine5',3'-tetraisopropyl disiloxane-riboguanosine(N-PAC)N2-Pac-3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-guanosineN2-Phenoxyacetyl-3′,5′-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine
Database identifiers
- CAS
131474-72-1
Properties
Physicochemical properties
- Density
- 1.32 · 1.32±0.1 g/cm3(Predicted)
- pka
- 8.83 · 8.83±0.20(Predicted)
Chemistry & industry
Applications
UsesN2-Phenoxyacetyl-3′,5′-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
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Compound notes
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