Pomalidomide-PEG3-C2-NH2
Basic information
- CAS
2446474-09-3- Standard SMILES
NCCOCCOCCOCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O- InChIKey
ALLUGXFCRRSPMS-UHFFFAOYSA-N- Molecular formula
- C21H28N4O7
- Average molar mass
- 448.5 g/mol
Names & identifiers
- Preferred name
- Pomalidomide-PEG3-C2-NH2
- IUPAC
- 4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
- English name
- Pomalidomide-PEG3-Amine HCl salt
- Molecular weight
- 484.93
Names & synonyms
Pomalidomide-PEG3-C2-NH22093416-31-8Pomalidomide 4'-PEG3-amineE3 ligase Ligand-Linker Conjugates 304-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneMFCD320634914-[[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione4-(12-amino-4,7,10-trioxa-1-azadodecan-1-yl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethylamino]-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione4-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethylamino]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dioneamino-PEG3-pomalidomidePomalidomide-PEG3-amine
Show more names
Pomalidomide-PEG3-C2-NH2 HClPomalidomide-PEG3-NH2.HClThalidomide-NH-PEG3-NH2 HClPomalidomide-PEG3-Amine HCl saltPomalidomide-PEG3-Amine hydrochloride4-(H2N-PEG3-CH2CH2NH)-Thalidomide HClPomalidomide-PEG3-C2-NH2 hydrochlorideThalidomide-NH-PEG3-C2-NH2 hydrochloridePomalidomide-NH-PEG3-amine hydrochloride
Pomalidomide Impurity 39orb1706411SCHEMBL19451340SCHEMBL29429853C21H28N4O7EX-A3945AKOS040743270E3 ligase Ligand-Linker Conjugates 30?
Database identifiers
- CAS
2446474-09-3
Properties
Computed structural properties
- XLogP
- -0.5
- Topological polar surface area
- 149 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 9
- Rotatable bonds
- 13
- Heavy atoms
- 32
- Formal charge
- 0
- Complexity
- 689
Physicochemical properties
- storage temp.
- 2 · 2-8°C
- form
- Solid
- color
- Light yellow to yellow
- InChI
- 1S/C21H28N4O7/c22-6-8-30-10-12-32-13-11-31-9-7-23-15-3-1-2-14-18(15)21(29)25(20(14)28)16-4-5-17(26)24-19(16)27/h1-3,16,23H,4-13,22H2,(H,24,26,27)
- InChIKey
- ALLUGXFCRRSPMS-UHFFFAOYSA-N
- SMILES
- O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCN)=CC=C3)=O)=O
- UNSPSC Code
- 12352116 · 12352116
- NACRES
- 21 · NA.21
- WGK Germany
- 3 · WGK 3
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- WGK 3
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
UsesPomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
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Compound notes
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