2-OTBS A(Ac) amidite
Basic information
- CAS
1220889-84-8- Standard SMILES
COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(C)=O)ncnc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1- InChIKey
IISGHHSYMWMWKH-FLEVKJGDSA-N- Molecular formula
- C48H64N7O8PSi
- Average molar mass
- 926.1 g/mol
Names & identifiers
- Preferred name
- 2-OTBS A(Ac) amidite
- IUPAC
- N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]acetamide
- English name
- Adenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(trimethylsilyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
- Molecular formula
- C48H64N7O8PSi
- Molecular weight
- 926.14
Names & synonyms
2-OTBS A(Ac) amidite1220889-84-8BP-433322'-O-TBDMS-Adenosine (N-Ac)-3'-CEP phosphoramidite(2R,3R,4R,5R)-5-(6-Acetamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite2'-O-TBDMS-A(Ac) CE PhosphoramiditeDMT-2'-O-TBDMS-A(Ac)-CE PhosphoramiditeDMT-2'-O-TBDMS-A(Ac)-CE Phosphoramidite1-((2R,4S,5R)-5-(1,3-diphenylimidazolidin-2-yl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dioneAdenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(trimethylsilyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramiditeAdenosine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(trimethylsilyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Database identifiers
- CAS
1220889-84-8
Properties
Computed structural properties
- Topological polar surface area
- 164 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 13
- Rotatable bonds
- 21
- Heavy atoms
- 65
- Formal charge
- 0
- Complexity
- 1,500
Physicochemical properties
- pka
- 9.48 · 9.48±0.43(Predicted)
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