Basic information
- CAS
191047-65-1- Standard SMILES
Oc1ncc(F)c(O)n1- InChIKey
GHASVSINZRGABV-UHFFFAOYSA-N- Molecular formula
- C4H3FN2O2
- Average molar mass
- 130.08 g/mol
Names & identifiers
- Preferred name
- 2,4-Pyrimidinediol, 5-fluoro- (9CI)
- English name
- 2,4-Pyrimidinediol, 5-fluoro- (9CI)
- Molecular formula
- C4H3FN2O2
- Molecular weight
- 130.08
Names & synonyms
5-fluoro-2,4-Pyrimidinediol2,4-Pyrimidinediol, 5-fluoro-2,4-Pyrimidinediol, 5-fluoro- (9CI)
Database identifiers
- CAS
191047-65-1
Properties
Physicochemical properties
- Boiling point
- 401.4 · 401.4±48.0 °C(Predicted)
- Density
- 1.69 · 1.690±0.06 g/cm3(Predicted)
- pka
- 1.57 · 1.57±0.10(Predicted)
Chemistry & industry
Suppliers1 total
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Additional notes
DefinitionChEBI: 5-fluorouracil is a nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth. It has a role as a xenobiotic, an environmental contaminant, a radiosensitizing agent, an antineoplastic agent, an immunosuppressive agent and an antimetabolite. It is a nucleobase analogue and an organofluorine compound. It is functionally related to a uracil.
Related reactions
0 records
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Compound notes
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