Methylamino-PEG2-t-butyl ester
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Basic information
- CAS
1807521-04-5- Standard SMILES
CNCCOCCOCCC(=O)OC(C)(C)C- InChIKey
AVMNTSUPHZLJHS-UHFFFAOYSA-N- Molecular formula
- C12H25NO4
- Average molar mass
- 247.33 g/mol
Names & identifiers
- Preferred name
- Methylamino-PEG2-t-butyl ester
- IUPAC
- tert-butyl 3-[2-[2-(methylamino)ethoxy]ethoxy]propanoate
- English name
- Methylamino-PEG2-t-butylester
- Molecular formula
- C12H25NO4
- Molecular weight
- 247.33
Names & synonyms
1807521-04-5Methylamino-PEG2-BocMethylamino-PEG2-t-butyl estertert-butyl 3-(2-(2-(methylamino)ethoxy)ethoxy)propanoateMFCD28155207MeNH-PEG2-CH2CH2COOtBuMethylamino-PEG2-t-butylestertert-butyl 3-[2-[2-(methylamino)ethoxy]ethoxy]propanoateTERT-BUTYL 3-{2-[2-(METHYLAMINO)ETHOXY]ETHOXY}PROPANOATEMeNH-PEG2-COOtBuMethylamino-PEG3-t-butylorb1989094
Show more names
CAS_1807521-04-5Methylamino-PEG3-t-butyl esterPropanoic acid, 3-[2-[2-(methylamino)ethoxy]ethoxy]-, 1,1-dimethylethyl esterMeNH-PEG2-CH2CH2COOtBu/ Propanoic acid, 3-[2-[2-(methylamino)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
SCHEMBL17503632HXC52104ZB0940AKOS030630007s10588BP-22383DA-55414MS-23504
Database identifiers
- CAS
1807521-04-5
Properties
Computed structural propertiesFilling in
- XLogP
- 0.3
- Topological polar surface area
- 56.8 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 11
- Heavy atoms
- 17
- Formal charge
- 0
- Complexity
- 201
Physicochemical properties
- Boiling point
- 315.5 · 315.5±22.0 °C(Predicted)
- Density
- 0.982 · 0.982±0.06 g/cm3(Predicted)
- storage temp.
- 2 · 2-8°C, protect from light
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 9.52 · 9.52±0.10(Predicted)
- form
- Oil
- color
- Colorless to light yellow
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
DescriptionMethylamino-PEG2-t-butyl ester is a PEG linker containing a methylamine group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The methylamine group is reactive with carboxylic acids, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
UsesMethylamino-PEG2-t-butyl Ester is a compound being used in studies for the preparation of maleimides as reagents for thiol conjugation.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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