5'-O-DMTr-N2-isobutyrylguanosine
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Basic information
- CAS
81246-83-5- Standard SMILES
COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]c(NC(=O)C(C)C)nc43)[C@H](O)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1- InChIKey
SSYBHRGSXXKZQZ-FKCALIPENA-N- Molecular formula
- C35H37N5O8
- Average molar mass
- 655.7 g/mol
Names & identifiers
- Preferred name
- 5'-O-DMTr-N2-isobutyrylguanosine
- English name
- 5'-O-DMTr-N2-isobutyrylguanosine
- Molecular formula
- C35H37N5O8
- Molecular weight
- 655.7
Names & synonyms
DMT-rG(iBu)5'-DMT-ibu-rG5'-O-DMT-ibu-rGN2-iBu-5'-O-DMT-guanosine5'-O-DMT-N2-ibu-Guanosine5’-O-DMTr-Guanosine (N-ibu)5'-O-DMTr-N2-isobutyrylguanosine5'-O-DMT-N2-Isobutyryl-GuanosineN2-isobutyryl-5'-O-(4,4'-dimethoxytrityl)guanosine5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-guanosine
Database identifiers
- CAS
81246-83-5
Properties
Physicochemical properties
- Melting point
- 153 °C · >153°C (dec.)
- Density
- 1.395 · 1.395±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 7.587 · 7.587±0.10(predicted)
- color
- Pale Yellow
- InChIKey
- SSYBHRGSXXKZQZ-FKCALIPENA-N
- SMILES
- O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](O)[C@@H]1O |&1:25,27,44,46,r|
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
Chemistry & industry
Applications
Uses5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-N-(2-methyl-1-oxopropyl)-guanosine is used to prepare ppGpp analogs as inhibitors of RelA from Gram-negative/-positive bacteria. It is also used to synthesize guanosine 5''-conjugates as initiator molecules for transcription priming.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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