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2-Ethoxyethyl methacrylate

HCID 178887362
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Basic information

CAS
35625-93-5
Standard SMILES
C=C(C)C(=O)OCCOCC
InChIKey
SFPNZPQIIAJXGL-UHFFFAOYSA-N
Molecular formula
C8H14O3
Average molar mass
158.19 g/mol

Overview

Based on available data, the CIR Expert Panel concluded that ... Ethoxyethyl Methacrylate is safe as used in nail enhancement products when skin contact is avoided. Products containing these ingredients should be accompanied with directions to avoid skin contact, because of the sensitizing potential of Methacrylates.

Names & identifiers

Preferred name
2-Ethoxyethyl methacrylate
IUPAC
2-ethoxyethyl 2-methylprop-2-enoate
English name
Poly(ethylene glycol) ethyl ether methacrylate
Molecular formula
(C2H4O)nC6H10O2
Molecular weight
0

Names & synonyms

2-Ethoxyethyl methacrylate2370-63-0Ethoxyethyl methacrylate2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester2-ethoxyethyl 2-methylprop-2-enoateMethacrylic acid, 2-ethoxyethyl ester5Q6XR4MR8EETHOXYETHYLMETHACRYLATENSC 241622-Ethoxyethyl Methacrylate (stabilized with MEHQ)51289-08-8DTXSID1022186
Show more names
Poly(ethylene glycol) ethyl ether methacrylatePOLY(ETHYLENE GLYCOL) ETHYL ETHER METHAC RYLATE, AVERAGE MN CA. 246Poly(oxy-1,2-ethanediyl), α-(2-methyl-1-oxo-2-propen-1-yl)-ω-ethoxy-
MFCD00009249NSC-24162NSC24162NCGC00166254-012-(ethyloxy)ethyl 2-methylprop-2-enoateBS-52221F712702-Ethoxyethyl Methacrylate, (stabilized with MEHQ)

Database identifiers

CAS
35625-93-5
ChEMBL
CHEMBL1414186
UNII
5Q6XR4MR8E
EC Number
219-135-3
Nikkaji
J109.532C

Properties

Computed structural properties

XLogP
1.4
Topological polar surface area
35.5 Ų
Hydrogen bond donors
0
Hydrogen bond acceptors
3
Rotatable bonds
6
Heavy atoms
11
Formal charge
0
Complexity
140

Experimental & physicochemical properties

PolymersPlastics & Rubber -> (Meth)acrylates
CosmeticsCosmetic ingredients (Ethoxyethyl Methacrylate) -> CIR (Cosmetic Ingredient Review)
Vapor Pressure1.1 [mmHg]
Physical Description · 2 items

Liquid

Colorless liquid with a fruity odor; [Atofina MSDS]

Physicochemical properties

Density
1.02 g/mL · 1.02 g/mL at 25 °C(lit.)
refractive index
20 · n20/D 1.445(lit.)
Flash point
230 °F · >230 °F
WGK Germany
1 · 1

Safety & regulation

Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.

GHS classification

GHS Classification · 6 items

Danger

H315 (23.8%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 172 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H227: Combustible liquid [Warning Flammable liquids]

Hazard information

Regulatory Information · 4 items

Chemical: 2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester

2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23190

2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester: Does not have an individual approval but may be used under an appropriate group standard

Other Safety InformationEvaluation - 2-Methoxyethyl methacrylate and 2-ethoxyethyl methacrylate
Hazards SummaryStabilized with 500 ppm butylated hydroxytoluene (CAS# 128-37-0); Causes essentially no eye and mild skin irritation in rabbits; Not a skin sensitizer in guinea pigs; [Atofina MSDS] See n-Butyl methacrylate.
Hazard Classes and Categories · 2 items

Skin Irrit. 2 (23.8%)

Flammable liquids - Category 4

Chemistry & industry

Uses & manufacturing

Uses · 2 items

CIR ingredient: Ethoxyethyl Methacrylate

Used as an intermediate; [Atofina MSDS]

U.S. Production2023: <50,000 lb
Industry UsesMonomers
General Manufacturing Information · 2 items

Pharmaceutical and Medicine Manufacturing

2-Propenoic acid, 2-methyl-, 2-ethoxyethyl ester: ACTIVE

Related reactions

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Compound notes

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Safety & protection

Protective Action Criteria (PAC) · 3 items

200 [mg/m3]

2200 [mg/m3]

13000 [mg/m3]

Toxicology

Toxicity Summary · 2 items

Based on available data, the CIR Expert Panel concluded that ... Ethoxyethyl Methacrylate is safe as used in nail enhancement products when skin contact is avoided. Products containing these ingredients should be accompanied with directions to avoid skin contact, because of the sensitizing potential of Methacrylates.

Safe for use in cosmetics, with qualifications

Safety data

wgk
1