(Ala13)-Apelin-13 (human, bovine, mouse, rat)
Basic information
- CAS
568565-11-7- Standard SMILES
CSCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)O- InChIKey
PZJZONZEQDOQAZ-COFPHXSQSA-N- Molecular formula
- C63H107N23O16S
- Average molar mass
- 1,474.7 g/mol
Names & identifiers
- Preferred name
- (Ala13)-Apelin-13 (human, bovine, mouse, rat)
- IUPAC
- (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]propanoic acid
- English name
- H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH
- Molecular formula
- C63H107N23O16S
- Molecular weight
- 1474.73
Names & synonyms
568565-11-7(Ala13)-Apelin-13(Ala13)-Apelin-13 (human, bovine, mouse, rat)H-GLN-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-ALA-OH[Ala13]-Apelin-13 trifluoroacetate saltH-QRPRLSHKGPMPA-OHorb1694642SCHEMBL31741399HY-P3162TXA56511AKOS040754605CS-0166698
Show more names
QRPRLSHKGPMPA[ALA13]-APELIN-13[Ala13]-Apelin-13 - 1 mg(Ala13)-Apelin-13 ，P1212[Ala13]Apelin 13 (human, mouse, rat, bovine)[Ala13]Apelin-13, human, bovine, mouse, rat (F13A) (2)(Ala??)-Apelin-13 (human, bovine, mouse, rat) acetate salt
T35374Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-AlaNH2-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala-OH
Properties
Computed structural properties
- XLogP
- -8.6
- Topological polar surface area
- 658 Ų
- Hydrogen bond donors
- 19
- Hydrogen bond acceptors
- 22
- Rotatable bonds
- 45
- Heavy atoms
- 103
- Formal charge
- 0
- Complexity
- 2,980
Physicochemical properties
- Density
- 1.52 · 1.52±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C
- pka
- 3.7 · 3.70±0.10(Predicted)
- form
- powder
- color
- white to beige
- Sequence
- Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala
- UNSPSC Code
- 51111800 · 51111800
- NACRES
- 77 · NA.77
- WGK Germany
- 3 · WGK 3
- Storage Class
- 11 · 11 - Combustible Solids
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- WGK 3
- Storage Class
- 11 - Combustible Solids
Chemistry & industry
Applications
Uses(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway[1].
Suppliers
Loading…
Open inquiries
Loading…
Related reactions
0 records
No reaction records under the current filter.
Compound notes
Loading…