Basic information
- CAS
130877-92-8- Standard SMILES
CCCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)NC(=O)[C@H](CCCC)NC(=O)[C@@H](NC(=O)[C@@H](N)CCCNC(=N)N)C(C)C)C(N)=O- InChIKey
SKVRTIXPQZQNMQ-APYWWOEASA-N- Molecular formula
- C40H66N12O11
- Average molar mass
- 891 g/mol
Names & identifiers
- Preferred name
- HIV Protease Substrate VI
- IUPAC
- (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-5-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
- English name
- HIV PROTEASE SUBSTRATE VI
- Molecular formula
- C40H66N12O11
- Molecular weight
- 891.03
Names & synonyms
HIV Protease Substrate VI130877-92-8HIVProteaseSubstrateVIArg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-5-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acidMFCD00237107H-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2orb2277369HY-P4466DA-54011FH108366CS-0654393
Show more names
ARG-VAL-NLE-P-NITRO-PHE-GLU-ALA-NLE-NH2H-ARG-VAL-NLE-PHE(4-NO2)-GLU-ALA-NLE-NH2L-Norleucinamide, L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-α-glutamyl-L-alanyl- (9CI)
HIV Protease Substrate VI (H-1148.0001)T80112
Properties
Computed structural properties
- XLogP
- -1.6
- Topological polar surface area
- 391 Ų
- Hydrogen bond donors
- 11
- Hydrogen bond acceptors
- 13
- Rotatable bonds
- 29
- Heavy atoms
- 63
- Formal charge
- 0
- Complexity
- 1,580
Physicochemical properties
- Density
- 1.38 · 1.38±0.1 g/cm3(Predicted)
- storage temp.
- -15 °C · -15°C
- pka
- 4.43 · 4.43±0.10(Predicted)
- Sequence
- 2 · Arg-Val-{Nle-p-nitro}-Phe-Glu-Ala-{Nle}-NH2
Chemistry & industry
Applications
UsesArg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 is a fluorogenic substrate of HIV-1 protease. Arg-Val-(Nle-p-nitro)-Phe-Glu-Ala-Nle-NH2 can be used to test HIV-1 protease activity[1].
Suppliers17 total
上海鸿肽生物科技有限公司15318089928 · [email protected]
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
凯试(上海)科技有限公司021-50135380 · [email protected]
Creative Peptides[email protected]
太原百利恒康生物技术有限公司19135651983 · [email protected]
杭州专肽生物技术有限公司17342063383 · [email protected]
南京肽谷生物科技有限公司18115476705 · [email protected]
成都云希化工有限公司+86-17380623303 · [email protected]
江西辐氨生物技术有限公司15002819872 · [email protected]
南京美韬医药科技有限公司[email protected] · [email protected]
上海瀚鸿科技股份有限公司021-54306202 18917919676 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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