Ceric ammonium nitrate

HCID 180504

Notes Reactions

Substructure search Find similar structures

Basic information

CAS: 10139-51-2
Standard SMILES: O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].O=[N+]([O-])[O-].[Ce+4].[NH4+].[NH4+]
InChIKey: XMPZTFVPEKAKFH-UHFFFAOYSA-P
Molecular formula: CeH8N8O18
Average molar mass: 548.22 g/mol
Monoisotopic mass: 547.9011

Names & identifiers

Preferred name: Ceric ammonium nitrate
IUPAC: diazanium;cerium(4+);hexanitrate
English name: Cerium(IV) ammonium nitrate
Molecular formula: CeH4N2O3
Molecular weight: 220.16

Names & synonyms

Cerium ammonium nitrateDiammonium hexanitratocerate10139-51-2U99S55ED6BNSC-215187RefChem:124502lambda4-cerium(4+) ion bis(nitric acid) diamine tetranitrate240-827-6Ammonium cerium nitrateAmmonium hexanitratocerateAmmonium hexanitratocerate(IV)Cerate(2-), hexakis(nitrato-kappaO)-, ammonium (1:2), (OC-6-11)-

Show more names

Ceric ammonium nitrateCeric(IV) ammonium nitrateAmmonium cerium IV Nitratediazanium;cerium(4+);hexanitrateSCHEMBL313904cerium (IV) diammonium nitratediammonium cerium (IV) nitratedi-ammonium cerium (IV) nitrate

Database identifiers

CAS: 10139-51-2、16774-21-3
PubChem CID: 180504
UNII: U99S55ED6B
EC Number: 240-827-6

Properties

Computed structural properties

Topological polar surface area: 379 Å²
Hydrogen bond donors: 2
Hydrogen bond acceptors: 18
Rotatable bonds: 0
Heavy atoms: 27
Formal charge: 0
Complexity: 18

Experimental & physicochemical properties

Physical DescriptionOrange solid, soluble in water; [Merck Index]

Physicochemical properties

FDA UNII: 99 S55ED6B · U99S55ED6B

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H272 (99.4%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]；H302 (92.6%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (67.4%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H315 (28%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (66.3%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H318 (68%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (29.1%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (26.9%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H400 (65.1%): Very toxic to aquatic life [Warning Hazardous to the aquatic environment, acute hazard]；H410 (65.7%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]

P210, P220, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P363, P370+P378, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 175 reports by companies from 19 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory InformationStatus: Active Update: 24-03-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/11355

Hazards SummarySee Cerium. See RARE EARTH METALS and linked occupational diseases.

Hazard Classes and CategoriesOx. Sol. 2 (99.4%)；Acute Tox. 4 (92.6%)；Skin Corr. 1B (67.4%)；Skin Irrit. 2 (28%)；Skin Sens. 1A (66.3%)；Eye Dam. 1 (68%)；Eye Irrit. 2 (29.1%)；STOT SE 3 (26.9%)；Aquatic Acute 1 (65.1%)；Aquatic Chronic 1 (65.7%)

Safety & protection

Protective Action Criteria (PAC) · 3 items

0.054 [mg/m3]

0.58 [mg/m3]

3.5 [mg/m3]

Toxicology

Treatment · 1 item

Methemoglobinemia can be treated with supplemental oxygen and methylene blue 1% solution administered intravenously slowly over five minutes followed by IV flush with normal saline. Methylene blue restores the iron in hemoglobin to its normal (reduced) oxygen-carrying state. (L1613)

Health EffectsNitrate and nitrite poisoning causes methemoglobinemia. Nitrites may cause pregnancy complications and developmental effects. They may also be carcinogenic. (L1137)

Adverse EffectsFibrogenic - Inducing tissue injury and fibrosis (scarring).

Exposure RoutesOral (L1137) ; inhalation (L1137)

Toxicity Summary · 1 item

Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and methemoglobin. This elevation of methemoglobin levels is a condition known as methemoglobinemia, and is characterized by tissue hypoxia, as methemoglobin cannot bind oxygen. (A2450, L1613)

Signs and Symptoms · 1 item

Nitrate and nitrite poisoning causes methemoglobinemia. Symptoms include cyanosis, cardiac dysrhythmias and circulatory failure, and progressive central nervous system (CNS) effects. CNS effects can range from mild dizziness and lethargy to coma and convulsions. (L1137)

Regulatory information

Regulatory InformationStatus: Active Update: 24-03-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/11355

Chemistry & industry

Pharmacology

Metabolism/Metabolites · 1 item

Intake of some amount of nitrates and nitrites is a normal part of the nitrogen cycle in humans. In vivo conversion of nitrates to nitrites can occur in the gastrointestional tract under the right conditions, significantly enhancing nitrates' toxic potency. The major metabolic pathway for nitrate is conversion to nitrite, and then to ammonia. Nitrites, nitrates, and their metabolites are excreted in the urine. (L1137)