1,2,3,4-Tetrahydro-1-naphthylamine

HCID 18066

Basic information

CAS
2217-40-5
Standard SMILES
NC1CCCc2ccccc21
InChIKey
JRZGPXSSNPTNMA-UHFFFAOYSA-N
Molecular formula
C10H13N
Average molar mass
147.22 g/mol
Monoisotopic mass
147.10479942

Names & identifiers

Preferred name
1,2,3,4-Tetrahydro-1-naphthylamine
IUPAC
1,2,3,4-tetrahydronaphthalen-1-amine
English name
1,2,3,4-Tetrahydro-1-naphthylamine
Molecular formula
C10H13N
Molecular weight
147.22

Names & synonyms

1,2,3,4-Tetrahydro-1-naphthylamine2217-40-51-AminotetralinO7A3GV2PNXNSC-30349DTXSID70903059RefChem:9066191-aminotetrahydronaphthaleneDTXCID00972455218-712-71,2,3,4-tetrahydronaphthalen-1-amineAminotetralin
Show more names
DASO-008AURORA KA-78181-tetralinamine1-AminotetralineAKOS BBS-00003619tetralin-1-ylamineac-α-Naphthylamine
(+/-)-1-aminotetralin1-Amino-1,2,3,4-tetrahydro-naphthaleneMFCD000017401-Amino-1,2,3,4-tetrahydronaphthalene1,2,3,4-tetrahydronaphthalen-1-ylamine1,2,3,4-tetrahydronaphthylaminetetralin-1-amine(+/-)-1,2,3,4-TETRAHYDRO-1-NAPHTHYLAMINE

Database identifiers

CAS
2217-40-5、2954-50-9
PubChem CID
18066
DTXSID
DTXSID70903059
UNII
O7A3GV2PNX
EC Number
218-712-7
Nikkaji
J135.688G

Properties

Computed structural properties

XLogP
1.6
Topological polar surface area
26 Ų
Hydrogen bond donors
1
Hydrogen bond acceptors
1
Rotatable bonds
0
Heavy atoms
11

Physicochemical properties

Boiling point
246 · 246-247 °C/714 mmHg (lit.)
Density
1.026 g/mL · 1.026 g/mL at 25 °C (lit.)
refractive index
20 · n20/D 1.562(lit.)
Flash point
230 °F · >230 °F
storage temp.
Keep in dark place,Inert atmosphere,Room temperature
form
Liquid

Safety & regulation

GHS classification

GHS Classification · 5 items

Danger

H302 (69.5%): Harmful if swallowed [Warning Acute toxicity, oral];H314 (69.5%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation];H315 (30.5%): Causes skin irritation [Warning Skin corrosion/irritation];H318 (69.5%): Causes serious eye damage [Danger Serious eye damage/eye irritation];H319 (30.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation];H335 (29.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation];H412 (69.5%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 151 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.;Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Hazard information

Regulatory InformationStatus: Active Update: 06-11-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/12079
Hazard Classes and CategoriesAcute Tox. 4 (69.5%);Skin Corr. 1C (69.5%);Skin Irrit. 2 (30.5%);Eye Dam. 1 (69.5%);Eye Irrit. 2 (30.5%);STOT SE 3 (29.8%);Aquatic Chronic 3 (69.5%)

Regulatory information

Regulatory InformationStatus: Active Update: 06-11-2012 https://echa.europa.eu/registration-dossier/-/registered-dossier/12079

Safety data

PPE
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
wgk
3
hs_code
29214500
risk_code
36/37/38
Signal word
Warning
Symbol(GHS)
GHS07

Chemistry & industry

Applications

Uses1,2,3,4-Tetrahydro-1-naphthylamine has been used in the preparation of new chiral phosphine-aminophosphine ligands.

General Description(R)-1,2,3,4-Tetrahydro-1-naphthylamine is an efficient reagent for iodocyclization of 4-aryl-4-pentenoic acids.

Suppliers100 total

国药集团化学试剂有限公司86-21-63210123 · [email protected]
常州帝通化工有限公司+86-0519-88298848 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]

Related reactions

194 records

Compound notes

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