Basic information
- CAS
37926-75-3- Standard SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)C3(F)[C@@H](O)C[C@]2(C)C1(O)C(=O)O- InChIKey
PFAGPIFFRLDBRN-PCCPBHLWSA-N- Molecular formula
- C21H27FO5
- Average molar mass
- 378.4 g/mol
- Monoisotopic mass
- 378.18425212
Names & identifiers
- Preferred name
- 9-Fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid
- IUPAC
- (8S,10S,11S,13S,14S,16S)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid
- English name
- (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylic acid
- Molecular formula
- C21H27FO5
- Molecular weight
- 378.44
Names & synonyms
37926-75-3DTXSID909589409-Fluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid(9xi)-9-Fluoro-11beta,17-dihydroxy-16beta-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acidBetamethasone 17-acidBetametasone Impurity 1Betamethasone Impurity 15Dexamethasone Impurity 97Betamethasone 17-Carboxylic AcidCocaine Hydrochloride Impurity 5-d3Betamethasone sodium phosphate impurity FBetamethasone Impurity 3 (Betamethasone 17-Carboxylic Acid)
Show more names
Betamethasone sodium phosphate degrades impurity 17-formic acidAndrosta-1,4-diene-17-carboxylic acid, 9-fluoro-11,17-dihydroxy-16-methyl-3-oxo-, (11β,16β,17α)-
Database identifiers
- CAS
37926-75-3
Properties
Computed structural properties
- XLogP
- 2
- Topological polar surface area
- 94.8 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 6
- Rotatable bonds
- 1
- Heavy atoms
- 27
- Formal charge
- 0
- Complexity
- 789
Physicochemical properties
- Boiling point
- 566.9 · 566.9±50.0 °C(Predicted)
- Density
- 1.35 · 1.35±0.1 g/cm3(Predicted)
- solubility
- Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 3.58 · 3.58±0.70(Predicted)
- color
- White to Off-White
- Stability
- Hygroscopic
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 280 · P280-P305+P351+P338
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P280-P305+P351+P338
Chemistry & industry
Applications
UsesBetamethasone Acid is a derivative of Betamethasone (B327000), a gluccocorticoid used as an anti-inflammatory agent.
Suppliers38 total
济南百隆化学有限公司[email protected] · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州佳途科技股份有限公司81960175-877 18933936954 · [email protected]
上海科骊科生物技术有限公司021-34975789 18721102763 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
廊坊市恒福源医药科技有限公司0316-2883537 19333636468 · [email protected]
上海柯维化学技术有限公司021-64609169 18901607656 · [email protected]
廊坊市泽康医药科技有限公司0316-2883536 19333636468 · [email protected]
深圳市星跃生物科技有限公司18124513697; 18124513697 · [email protected]
Moxin Chemicals+86-17320513646 +86-17320513646 · [email protected]
杭州云易国科生物科技有限公司18457506494 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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