Basic information
- CAS
3055-96-7- Standard SMILES
CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCO- InChIKey
OJCFEGKCRWEVSN-UHFFFAOYSA-N- Molecular formula
- C24H50O7
- Average molar mass
- 450.6 g/mol
- Monoisotopic mass
- 450.35565393
Overview
The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Laureth-6...
Names & identifiers
- Preferred name
- 3,6,9,12,15,18-Hexaoxatriacontan-1-ol
- IUPAC
- 2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanol
- English name
- Hexaethylene glycol monododecyl ether
- Molecular formula
- C24H50O7
- Molecular weight
- 450.65
Names & synonyms
3055-96-73,6,9,12,15,18-Hexaoxatriacontan-1-olHexaoxyethylene dodecyl etherPEG-6 Lauryl etherJ2N33740SHRefChem:91677n-dodecyl hexaoxyethylene glycol ether221-282-3Hexaethylene glycol monododecyl etherLaureth-6Hexaethylene glycol dodecyl etherLauryl hexaethoxylate
Show more names
C12E6Hexaethylene glycol monolauryl etherhexaethyleneDODECYLHEXAGLYCOLn-dodecyl-PEG6-OHlaurylhexaethoxylatedodecylhexaethyleneglycolhexaethyleneglycollaurylether
Dodecyl hexaethylene glycolHEXAETHYLENEGLYCOLMONODODECYLETHERHexaethylene glycol lauryl etherHexaoxyethylene dodecyl monoetherHexa(oxydiethanol) monodecyl etherEINECS 221-282-3UNII-J2N33740SHDODECYL HEXAOXYETHYLENE MONOETHER
Database identifiers
- CAS
3055-96-7- PubChem CID
- 18282
- DTXSID
DTXSID6058633- ChEMBL
CHEMBL4758406- EC Number
- 221-282-3
- Nikkaji
- J77.657B
Properties
Computed structural properties
- XLogP
- 4.4
- Topological polar surface area
- 75.6 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 28
- Heavy atoms
- 31
- Formal charge
- 0
- Complexity
- 306
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Laureth-6) -> CIR (Cosmetic Ingredient Review)
Surfactant; Emulsifying
SurfactantsSurfactant
LogP4.81
Physicochemical properties
- Melting point
- 27 ℃ · approximate 27℃
- Boiling point
- 210 · 210-215 °C(Press: 0.05 Torr)
- Density
- 0.965 · 0.965~0.971g/ml (35℃)
- refractive index
- 1.447 · 1.447~1.453 (35℃/D)
- Flash point
- 26 °C · 26 °C
- storage temp.
- 2 · 2-8°C
- form
- semisolid
- pka
- 14.36 · 14.36±0.10(Predicted)
- color
- White or Colorless to Almost white or Almost colorless
- BRN
- 1715367 · 1715367
- Stability
- Stable. Incompatible with strong oxidizing agents. Combustible.
- Cosmetics Ingredients Functions
- SURFACTANT - CLEANSINGSURFACTANT - EMULSIFYING
- Cosmetic Ingredient Review (CIR)
- HEXAETHYLENE GLYCOL MONODODECYL ETHER (3055-96-7)
- InChI
- 1S/C24H50O7/c1-2-3-4-5-6-7-8-9-10-11-13-26-15-17-28-19-21-30-23-24-31-22-20-29-18-16-27-14-12-25/h25H,2-24H2,1H3
- InChIKey
- OJCFEGKCRWEVSN-UHFFFAOYSA-N
- SMILES
- CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCO
- LogP
- 3.26 · 3.260 (est)
- CAS DataBase Reference
- 3055 · 3055-96-7(CAS DataBase Reference)
- EWG's Food Scores
- 1 · 1-3
- FDA UNII
- 2 N33740SH · J2N33740SH
- UNSPSC Code
- 12161900 · 12161900
- NACRES
- 25 · NA.25
- Symbol(GHS)
- 5 · GHS05,GHS07,GHS09
- Signal word
- Danger
- Hazard statements
- 302 · H302-H318-H400
- Precautionary statements
- 273 · P273-P280-P301+P312+P330-P305+P351+P338+P310
- PPE
- 95 · dust mask type N95 (US), Eyeshields, Gloves
- Hazard Codes
- Xn,N
- Risk Statements
- 22 · 22-41-50
- Safety Statements
- 26 · 26-39-61
- RIDADR
- 3077 · UN 3077 9/PG 3
- WGK Germany
- 2 · 2
- RTECS
- 4780500 · MP4780500
- F
- 3 · 3
- HS Code
- 2909.49 · 2909.49.6000
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 4 OralAquatic · Acute Tox. 4 OralAquatic Acute 1Eye Dam. 1
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Danger
H302 (97.6%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P273, P280, P301+P317, P305+P354+P338, P317, P330, P391, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Regulatory Information3,6,9,12,15,18-Hexaoxatriacontan-1-ol: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesAcute Tox. 4 (97.6%)
Toxicology
Toxicity Summary
The CIR Expert Panel concluded that the alkyl PEG ethers, listed below, are safe in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating. This assessment is also intended to address future alkyl PEG ether cosmetic ingredients that vary from those ingredients recited herein only by the number of ethylene glycol repeat units...Laureth-6...
Safe for use in cosmetics, with qualifications
Safety data
- F
- 3
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 2
- rtecs
- MP4780500
- ridadr
- UN 3077 9/PG 3
- hs_code
- 2909.49.6000
- risk_code
- 22-41-50
- Signal word
- Danger
- Symbol(GHS)
- GHS05,GHS07,GHS09
- hazard_code
- Xn,N
- safety_code
- 26-39-61
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H318-H400
- Hazard Classifications
- Acute Tox. 4 OralAquatic Acute 1Eye Dam. 1
- Precautionary statements
- P273-P280-P301+P312+P330-P305+P351+P338+P310
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Laureth-6
Use ClassificationCosmetics -> Surfactant; Emulsifying
Applications
UsesHexaethylene glycol monododecyl ether is a nonionic surfactant.
Suppliers56 total
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
湖北永阔科技有限公司027-59223108 15972152991 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
广州鸿远生物科技有限公司15817493340 · [email protected]
上海仲因实业有限公司2537653158 16621191650 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Aladdin Scientific[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
广东谦进化学试剂有限公司0751-2818792 13435114148 · [email protected]
湖北成海化工有限公司027-59220433 18327245847 · [email protected]
郑州泰丰制药有限公司182-3786-0830 19913859908 · [email protected]
山东西亚化学有限公司13355009207 13355009207 · [email protected]
上海和宁美生物医药科技有限公司021-18019086215 18019086215 · [email protected]
浙江瑞奥生物科技有限公司82087565 15757883359 · [email protected]
江苏艾康生物医药研发有限公司025-66113011 13913916777 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
陕西麟邦实业有限公司17709134430 · [email protected]
PT CHEM GROUP LIMITED+86-85511178; +86-85511178 · [email protected]
上海研纷生化科技有限公司13611955358 15002190549 · [email protected]
池州凯隆进出口贸易有限公司[email protected]
九鼎化学（上海）科技有限公司4009209199 · [email protected]
南京佰瑞利康生物科技有限公司18168036974 · [email protected]
安那莱（齐河）新材料科技有限公司18600642180（微信同） 13391601435 · [email protected]
成都润泽本土化工有限公司028-88469284 18000562381 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
成都标样生物科技有限公司028-81700200 13308200041 · [email protected]
上海颖心实验室设备有限公司021-021-59178156 15300768757 · [email protected]
成都华纯科技有限公司400-1166-196 15982826727 · [email protected]
山东小野化学股份有限公司0539-6362799 20）
Shanghai Acmec Biochemical Technology Co., Ltd.+86-18621343501 · [email protected]
上海泰坦科技股份有限公司13023226327 · [email protected]
杭州洁汉化工有限公司+86-571-86217390; +8618058761490 · [email protected]
上海臻励生物科技有限公司021-16621358918; 18516310516;16621358918;13045646768 · [email protected]
西安康福诺生物科技有限公司+86-156-80926068 +86-15680926068 · [email protected]
上海皓鸿生物医药科技有限公司400-8210725 400821072 · [email protected]
厦门盈融达化工有限公司+86-0592-6210733 · [email protected]
TCI Chemicals (India) Pvt. Ltd.[email protected]
万欣生物科技（嘉兴）有限公司0573-83568680 18057391398 · [email protected]
河南阿尔法化工有限公司0371-55055611 18137792234 · [email protected]
上海康恩博医药科技有限公司（科小研试剂）400-1388-521 17510465506 · [email protected]
山东博宇生物技术有限公司13356310019 13356310019 · [email protected]
广东元丰化学试剂有限公司0751-2829979 13318584237 · [email protected]
SHANGHAI KEAN TECHNOLOGY CO., LTD.+8613817748580 · [email protected]
BOC Sciences+1-631-485-4226 · [email protected]
广东翁江化学试剂有限公司0751-2815983 13927872582 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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