Basic information
- CAS
1188-37-0- Standard SMILES
CC(=O)NC(CCC(=O)O)C(=O)O- InChIKey
RFMMMVDNIPUKGG-UHFFFAOYSA-N- Molecular formula
- C7H11NO5
- Average molar mass
- 189.17 g/mol
- Monoisotopic mass
- 189.06372245
Overview
Acetyl-Glu is a glutamic acid derivative.
Names & identifiers
- Preferred name
- N-acetylglutamic acid
- IUPAC
- 2-acetamidopentanedioic acid
- English name
- N-Acetyl-L-glutamic acid
- Molecular formula
- C7H11NO5
- Molecular weight
- 189.17
Names & synonyms
N-acetylglutamic acidDTXSID00859595RefChem:927033DTXCID002025022-acetamidopentanedioic acid5817-08-3N-Acetyl-DL-glutamic acidAc-DL-Glu-OHACEGLUMATEDL-Acetylglutamic acidMFCD00063195(R)-2-Acetamidopentanedioic acid
Show more names
N-Acetyl-L-glutamaten-acetylglutamateNAcGluAC-GLU-OHN-AC-L-GLUN-Ac-Glu-OHAc-L-Glu-OHl-glutamicaciN-Ac-L-Glu-OH
Glutamic acid, N-acetyl-Acetyl-DL-glutamic acid(S)-2-acetamidopentanedioic acidacetyl-gluMaybridge1_0025212-acetamidopentanedioicacid339072-10-5MLS002207281
Database identifiers
- CAS
1188-37-0、5817-08-3- PubChem CID
- 185
- DTXSID
DTXSID00859595- ChEMBL
CHEMBL2142890- ChEBI
CHEBI:172431
Properties
Computed structural properties
- XLogP
- -1.8
- Topological polar surface area
- 104 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 5
- Heavy atoms
- 13
- Formal charge
- 0
- Complexity
- 225
Experimental & physicochemical properties
CosmeticsSkin conditioning
Physicochemical properties
- Melting point
- 194 · 194-196 °C(lit.)
- alpha
- -16 · -16 º (c=1, water)
- Boiling point
- 324.41 °C · 324.41°C (rough estimate)
- Density
- 1.4119 · 1.4119 (rough estimate)
- FEMA
- 4752 · 4752 | N-ACETYL GLUTAMATE
- refractive index
- -15 ° · -15 ° (C=1, H2O)
- storage temp.
- 2 · 2-8°C
- solubility
- 36 g/l · 36g/l (Lit.)
- pka
- 3.45 · 3.45±0.10(Predicted)
- form
- Solid
- color
- White
- optical activity
- 22 · [α]22/D 15.6°, c = 1 in H2O
- Water Solubility
- 2.7 g/100 · 2.7 g/100 mL (20 ºC)
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 93.8% (15 of 16) of all reports.
Not Classified
Aggregated GHS information provided per 16 reports by companies from 2 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory InformationREACH registered substance: N-acetylglutamic acid (EC: 214-708-4)
Hazard Classes and CategoriesNot Classified
Safety data
- wgk
- 2
- tsca
- TSCA listed
- rtecs
- LZ9725000
- hs_code
- 29241900
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- safety_code
- 24/25
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302-H315-H319-H335
- REACH Registrations
- Active
- Precautionary statements
- P271-P261-P280
Chemistry & industry
Uses & manufacturing
Use ClassificationCosmetics -> Skin conditioning
General Manufacturing InformationGlutamic acid, N-acetyl-: INACTIVE
Applications
UsesN-Acetyl-L-glutamic Acid is the N-Acetyl analogue of the non-essential amino acid, L-glutamic acid (G596960). N-Acetyl-L-glutamic Acid activates carbamoyl phosphate synthetase in the urea cycle.
UsesSubstrate for acetylglutamate kinase. Inhibitor of N-acetyl-L-glutamate synthetase
UsesN-Acetyl-L-glutamic acid is used as pharmaceutical intermediates.
Suppliers100 total
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
南京一化生物科技有限公司18168057470 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]
北京安司莫森技术有限公司010-82954736 13391601435 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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