Basic information
- CAS
60687-36-7- Standard SMILES
C[C@H](N)P(=O)(O)O- InChIKey
UIQSKEDQPSEGAU-UWTATZPHSA-N- Molecular formula
- C2H8NO3P
- Average molar mass
- 125.06 g/mol
- Monoisotopic mass
- 125.02418011
Overview
(R)-(1-aminoethyl)phosphonic acid is an optically active phosphonic acid having a 1-aminoethyl group attached to the phosphorus. It is a member of phosphonic acids and a primary amino compound. It is functionally related to a phosphonic acid. It is an enantiomer of a (S)-(1-aminoethyl)phosphonic acid.
Names & identifiers
- Preferred name
- 1-Aminoethylphosphonic acid, (R)-
- IUPAC
- [(1R)-1-aminoethyl]phosphonic acid
- English name
- (R)-(-)-1-Aminoethyl-phosphonic acid
- Molecular formula
- C2H8NO3P
- Molecular weight
- 125.06
Names & synonyms
(R)-(-)-1-Aminoethylphosphonic acidL-1-Aminoethylphosphonic acidL-ALA-P1-Aminoethylphosphonic acid, (R)-L-FOSFALINPhosphonic acid, ((1R)-1-aminoethyl)-FF820GN7Q4(R)-(-)-(1-aminoethyl)phosphonic acidJ282.319EPHOSPHONIC ACID, P-((1R)-1-AMINOETHYL)-Phosphonic acid, [(1R)-1-aminoethyl]-RefChem:429426
Show more names
L-ALA(P)H-R-ALA(P)-OHH-D-ALAP-(OH)2H-D-AETPO-(OH)2(1R)-1-PHOSPHONO-1-ETHANAMINE(R)-(-)-1-PHOSPHONOETHYLAMINED-1-AMINO-ETHYLPHOSPHONIC ACID(R)-1-AMINO-ETHYLPHOSPHONIC ACIDL(-)-1-AMINOETHYLPHOSPHONIC ACID?-(-)-1-Aminoethylphosphonic acid
621-368-460687-36-7[(1r)-1-aminoethyl]phosphonic acid(R)-(1-aminoethyl)phosphonic acidD-(1-Aminoethyl)phosphonic acid1-Aminoethylphosphonate(1R)-1-aminoethylphosphonic acid(R)-(1-Aminoethyl)phosphonsaeure
Database identifiers
Properties
Computed structural properties
- XLogP
- -4.3
- Topological polar surface area
- 83.6 Ų
- Hydrogen bond donors
- 3
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 7
- Formal charge
- 0
- Complexity
- 97.1
Physicochemical properties
- Melting point
- 290 °C · 290 °C (dec.)(lit.)
- storage temp.
- 2 · 2-8°C
- form
- crystalline powder
- color
- White
- optical activity
- 20 · [α]20/D -4.8±0.5°, c =5% in H2O
- InChI
- 1S/C2H8NO3P/c1-2(3)7(4,5)6/h2H,3H2,1H3,(H2,4,5,6)/t2-/m1/s1
- InChIKey
- UIQSKEDQPSEGAU-UWTATZPHSA-N
- SMILES
- C[C@H](N)P(O)(O)=O
- FDA UNII
- 820 GN7Q4 · FF820GN7Q4
- UNSPSC Code
- 12352116 · 12352116
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 315 · H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
- target organs
- Respiratory system
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 42 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Safety data
- PPE
- dust mask type N95 (US), Eyeshields, Gloves
- wgk
- 3
- ridadr
- 3261
- hs_code
- 2931499090
- risk_code
- 36/37/38
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xi
- safety_code
- 26-36
- Storage Class
- 11 - Combustible Solids
- target organs
- Respiratory system
- Hazard statements
- H315-H319-H335
- Hazard Classifications
- Eye Irrit. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
UsesDi- to tetrapeptides with this amino acid analogue at the "P-terminal" are bactericides and synergistic potentiators of penicillins and cephalophorins
Uses(R)-()-1-Aminoethylphosphonic acid can be used to prepare copper(II) heteroligand complexes, which are employed in the solution equilibrium studies.
General Description(R)-(-)-1-Aminoethylphosphonic acid is a synthetic analog of L-alanine that shows antibacterial property.
Suppliers13 total
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
石家庄州昆医药科技有限公司0311-83784138 18633934202 · [email protected]
上海遐瑞医药科技有限公司+86 21 61551611
广州爱纯医药科技有限公司020-39119399 18927568969 · [email protected]
上海馨远医药科技有限公司021-24206007 13764915196 · [email protected]
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司021-61415566 800-8193336 · [email protected]
上海颖心实验室设备有限公司021-021-59178156 15300768757 · [email protected]
杭州洁汉化工有限公司+86-571-86217390; +8618058761490 · [email protected]
Capot Chemical Co.,Ltd.+86-（0）57185586718 +86-13336195806 · [email protected]
西安敏则医药科技有限公司
Related reactions
0 records
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Compound notes
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