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Basic information
- CAS
172922-91-7- Standard SMILES
O=Cc1c2[nH]c3ccccc3c2cc2[nH]c3ccccc3c12- InChIKey
ZUDXFBWDXVNRKF-UHFFFAOYSA-N- Molecular formula
- C19H12N2O
- Average molar mass
- 284.3 g/mol
- Monoisotopic mass
- 284.09496301
Names & identifiers
- Preferred name
- 6-Formylindolo(3,2-b)carbazole
- IUPAC
- 5,11-dihydroindolo[3,2-b]carbazole-12-carbaldehyde
- English name
- 6-ForMylindolo[3,2-b]carbazole
- Molecular formula
- C19H12N2O
- Molecular weight
- 284.31
Names & synonyms
FICZ172922-91-75,11-dihydroindolo[3,2-b]carbazole-6-carbaldehyde5,11-dihydroindolo[3,2-b]carbazole-12-carbaldehydeDTXSID302743385,11-Dihydroindolo(3,2-b)carbazole-6-carbaldehydeFICZ-carbazole5,11-dihydroindolo(3,2-b)carbazole-12-carbaldehydeRefChem:104663DTXCID60225818683-412-96-Formylindolo(3,2-b)carbazole
Show more names
FICZ, 10 mM in DMSO6-FORMYLINDOLO A CARBAZOLE6-Formylindolo[3,2-b]carbazole (FICZ)Indolo[3,2-b]carbazole-6-carbaldehyde5H,11H-indolo[3,2-b]carbazole-6-carbaldehyde5,11-Dihydroindolo[3,2-b]carbazole-6-carboxaldehydeinhibit,Inhibitor,Aryl Hydrocarbon Receptor,AhR,FICZ
229020-82-0MFCD09879259CHEMBL4720316-FORMYLINDOLO [3,2-B] CARBAZOLEIndolo[3,2-b]carbazole-6-carboxaldehyde, 5,11-dihydro-Bio1_000123A1LWISpectrum5_001953
Database identifiers
- CAS
172922-91-7、229020-82-0- PubChem CID
- 1863
- DTXSID
DTXSID30274338- ChEMBL
CHEMBL472031- ChEBI
CHEBI:94466- EC Number
- 683-412-9
- Nikkaji
- J938.248H
Properties
Computed structural propertiesFilling in
- XLogP
- 4.3
- Topological polar surface area
- 48.7 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 1
- Heavy atoms
- 22
- Formal charge
- 0
- Complexity
- 453
Physicochemical properties
- Boiling point
- 630.3 · 630.3±35.0 °C(Predicted)
- Density
- 1.463 · 1.463±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C
- solubility
- Soluble in DMSO (up to 10 mg/ml).
- form
- powder
- pka
- 15.66 · 15.66±0.30(Predicted)
- color
- yellow to orange
- Stability
- 1 year · Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
- InChI
- InChI=1S/C19H12N2O/c22-10-14-18-12-6-2-4-8-16(12)20-17(18)9-13-11-5-1-3-7-15(11)21-19(13)14/h1-10,20-21H
- InChIKey
- ZUDXFBWDXVNRKF-UHFFFAOYSA-N
- SMILES
- N1C2=C(C=CC=C2)C2=C1C(C=O)=C1C3=C(NC1=C2)C=CC=C3
- UNSPSC Code
- 12352200 · 12352200
- NACRES
- 77 · NA.77
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 301 · P301+P312+P330
- WGK Germany
- 1 · 1
- Storage Class
- 11 · 11 - Combustible Solids
- Hazard Classifications
- 4 Oral · Acute Tox. 4 Oral
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 1
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Storage Class
- 11 - Combustible Solids
- Hazard statements
- H302
- Hazard Classifications
- Acute Tox. 4 Oral
- Precautionary statements
- P301+P312+P330
Chemistry & industry
Applications
Description6-Formylindolo(3,2-b)carbazole (FICZ) (172922-91-7) is a very potent (Kd= 0.07 nM) endogenous ligand for the aryl hydrocarbon receptor (AhR).1,2
Uses6-Formylindolo[3,2-b]carbazole is a tryptophan photoproduct, suppresses pulmonary eosinophilia and Th2-type cytokine production in a mouse model of ovalbumin-induced allergic asthma.
Suppliers2 total
斯百全化学（上海）有限公司021-021-021-67601398-809-809-809 15221380277 · [email protected]
上海腾骞生物科技有限公司021-50895067 18616507272;13681616114;15020344067 · [email protected]
Related reactions
0 records
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Compound notes
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