Basic information
- CAS
4701-54-6- Standard SMILES
CC(C)=CCCC1=C2C(C)C(OC1=O)[C@@]1(C)[C@H]2C[C@@H](O)[C@@H]2[C@@H]1CCC1[C@H](C)[C@H](O)CC[C@@]12C- InChIKey
VJLJIUMMRHGGOQ-NLANOYDCSA-N- Molecular formula
- C29H44O4
- Average molar mass
- 456.7 g/mol
- Monoisotopic mass
- 456.32395988
Names & identifiers
- Preferred name
- 3,11-Dihydroxy-4,14,16-trimethyl-15,21-epoxy-18-norcholesta-17,24-dien-21-one
- IUPAC
- (2R,3S,7S,8R,11S,12R,13R,15S)-8,13-dihydroxy-2,7,11,20-tetramethyl-17-(4-methylpent-3-enyl)-19-oxapentacyclo[14.3.1.02,15.03,12.06,11]icos-16-en-18-one
- English name
- 16-O-deacetylfusidic acid lactone
- Molecular formula
- C29H44O4
- Molecular weight
- 456.67
Names & synonyms
DTXSID609637233,11-Dihydroxy-4,14,16-trimethyl-15,21-epoxy-18-norcholesta-17,24-dien-21-one3alpha,11alpha-Dihydroxy-4alpha,14,16-trimethyl-8alpha,9beta,13alpha,14beta-15,21-epoxy-18-norcholesta-17,24-dien-21-one-LactoneFucidic acid EP impurity KFusidic Acid BP Impurity?KSodium Fusidate Impurity KFosfide acid EP impurity KFusidic Acid Impurity K(EP)16-Deacetylfusidic Acid γ-Lactone16-O-deacetylfusidic acid lactoneDeacetylfusidic acid 21,16-lactone
Show more names
16-Deacetylfusidic Acid gamma-Lactone
Database identifiers
- CAS
4701-54-6- PubChem CID
- 193397
- DTXSID
DTXSID60963723
Properties
Computed structural properties
- XLogP
- 5.8
- Topological polar surface area
- 66.8 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 33
- Formal charge
- 0
- Complexity
- 884
Physicochemical properties
- Boiling point
- 597.4 · 597.4±50.0 °C(Predicted)
- Density
- 1.14 · 1.14±0.1 g/cm3(Predicted)
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 14.69 · 14.69±0.70(Predicted)
- color
- White to Off-White
Chemistry & industry
Applications
Uses16-Deacetylfusidic Acid γ-Lactone is a metabolite of the drug Fusidic Acid (F865500). Fusidic acid is a bacteriostatic antibiotic. Fusidic Acid suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
Suppliers47 total
天津始加生物医药科技有限公司15022261580 · [email protected]
广州隽沐生物科技股份有限公司020-36607679; 13502246435 · [email protected]
广州隽唐科技有限公司020-36607679 13502246435 · [email protected]
广州蓝宁生物科技有限公司15813355568 · [email protected]
Sinco Pharmachem (ShenZhen) R&D Co., Ltd.+86-18603013401 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
廊坊市恒福源医药科技有限公司0316-2883537 19333636468 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
希瓦生物科技（广州）有限公司13268215580 · [email protected]
上海柯维化学技术有限公司021-64609169 18901607656 · [email protected]
佛山宝诺生物科技有限公司0757-85921206 18520245316 · [email protected]
Related reactions
0 records
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Compound notes
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