Tetrasodium Etidronate
Basic information
- CAS
29329-71-3- Standard SMILES
CC(O)(P(=O)([O-])[O-])P(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]- InChIKey
KWXLCDNSEHTOCB-UHFFFAOYSA-J- Molecular formula
- C2H4Na4O7P2
- Average molar mass
- 293.96 g/mol
- Monoisotopic mass
- 293.90230359
Overview
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Names & identifiers
- Preferred name
- Tetrasodium Etidronate
- IUPAC
- tetrasodium;1,1-diphosphonatoethanol
- English name
- (1-Hydroxyethylidene)bis-phosphonic acid tetrasodium salt
- Molecular formula
- C2H9NaO7P2
- Molecular weight
- 230.02
Names & synonyms
3794-83-0Tetrasodium etidronateTarpinel 4NLTurpinal 4NLSequion 10Na4etidronate tetrasodiumDefloc EN 43Dequest 2016UNII-CZZ9T1T1X4EINECS 223-267-7CZZ9T1T1X4Tetrasodium 1-hydroxyethylidene-1,1-diphosphonate
Show more names
HEDP.NA4hydroxyethylidene diphosphonateSodium Salt of 1-Hydroxyethylene -1, 1,-Diphosphonic Acid HEDP.4NaHEDO.NA4deflocen43dequest2016tarpinel4nlturpinal4nlsequion10na4hedp tetrasodium salt
(1-Hydroxyethylidene)diphosphonic acid, tetrasodium saltEthane-1-hydroxy-1,1-diphosphonic acid, tetrasodium salt1-Hydroxyethylidene-1,1-diphosphonic acid, tetrasodium saltDTXSID7029663Tetrasodium 1-hydroxyethane-1, 1-diphosphonateEC 223-267-7ETIDRONATE TETRASODIUM [WHO-DD](1-Hydroxyethylidene)bisphosphonic acid, tetrasodium salt
Database identifiers
- CAS
29329-71-3、3794-83-0
Properties
Computed structural properties
- Topological polar surface area
- 147 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 7
- Rotatable bonds
- 0
- Heavy atoms
- 15
- Formal charge
- 0
- Complexity
- 188
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Tetrasodium Etidronate) -> CIR (Cosmetic Ingredient Review)
Chelating; Viscosity controlling; Emulsion stabilizing
Physical DescriptionLiquid; Dry Powder
Physicochemical properties
- Density
- 2.074 · 2.074[at 20℃]
- vapor pressure
- 0 Pa · 0Pa at 25℃
- solubility
- Aqueous Acid (Slightly), Water (Sparingly)
- pka
- 2.18 · 2.18[at 20 ℃]
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 774 g/L · 774g/L at 20℃
- Stability
- Hygroscopic
- Cosmetics Ingredients Functions
- CHELATINGEMULSION STABILISINGVISCOSITY CONTROLLING
- InChI
- InChI=1S/C2H8O7P2.Na.H/c1-2(3,10(4,5)6)11(7,8)9;;/h3H,1H3,(H2,4,5,6)(H2,7,8,9);;
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 0.8% (6 of 738) of reports.
Warning
H302 (83.6%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P264+P265, P270, P280, P301+P317, P305+P351+P338, P330, P337+P317, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 738 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Warning
Hazard information
Regulatory Information
Chemical: Phosphonic acid, (1-hydroxyethylidene)bis-, tetrasodium salt
Chemical: Phosphonic acid, (1-hydroxyethylidene)bis-, sodium salt
Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:4) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:4) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: Tetrasodium (1-hydroxyethylidene)bisphosphonate (EC: 223-267-7)
Phosphonic acid, (1-hydroxyethylidene)bis-, sodium salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Etidronate tetrasodium: Does not have an individual approval but may be used under an appropriate group standard
Other Safety Information
IMAP assessments - Etidronic acids: Human health tier II assessment
IMAP assessments - Etidronic acids: Human health tier II assessment
Hazard Classes and Categories
Acute Tox. 4 (83.6%)
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Tetrasodium Etidronate
U.S. Production2023: 415,885 lb
Consumer UsesDispersing agent
Industry UsesAnti-scaling agent
Household ProductsInformation on 125 consumer products that contain Tetrasodium etidronate in the following categories is provided:
Use ClassificationCosmetics -> Chelating; Viscosity controlling; Emulsion stabilizing
General Manufacturing Information
Construction
Phosphonic acid, P,P'-(1-hydroxyethylidene)bis-, sodium salt (1:4): ACTIVE
Applications
Uses(1-Hydroxyethylidene)bis-phosphonic Acid Tetrasodium Salt is used in method for applying a gel compound on a surface of a device and corresponding coated device.
Upstream & downstream products
Upstream raw materials
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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