Basic information
- CAS
127063-08-5- Standard SMILES
CCC[C@@H](NC(=O)N1C(=O)C(CC)(CC)[C@@H]1Oc1ccc(CC(=O)O)cc1)c1ccc(C)cc1- InChIKey
KGAREWFAONZBOP-RDGATRHJSA-N- Molecular formula
- C27H34N2O5
- Average molar mass
- 466.6 g/mol
- Monoisotopic mass
- 466.24677219
Overview
potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase; structure given in first source
Names & identifiers
- Preferred name
- L 680833
- IUPAC
- 2-[4-[(2S)-3,3-diethyl-1-[[(1R)-1-(4-methylphenyl)butyl]carbamoyl]-4-oxoazetidin-2-yl]oxyphenyl]acetic acid
- English name
- L 680833
- Molecular formula
- C27H34N2O5
- Molecular weight
- 466.575
Names & synonyms
127063-08-5L 680833L-680,833RefChem:151676L-680833CHEMBL937272-[4-[(2S)-3,3-diethyl-1-[[(1R)-1-(4-methylphenyl)butyl]carbamoyl]-4-oxoazetidin-2-yl]oxyphenyl]acetic acid2-(4-(((S)-3,3-Diethyl-4-oxo-1-(((R)-1-(p-tolyl)butyl)carbamoyl)azetidin-2-yl)oxy)phenyl)acetic acidBenzeneacetic acid, 4-[[(2S)-3,3-diethyl-1-[[[(1R)-1-(4-methylphenyl)butyl]amino]carbonyl]-4-oxo-2-azetidinyl]oxy]-orb1703214SCHEMBL7374538DTXSID10925775
Show more names
833L680L-680L 680
GLXC-24003BDBM50286252AKOS030583550HY-120876T24328(4-{[(2S)-3,3-Diethyl-1-(hydroxy{[(1R)-1-(4-methylphenyl)butyl]imino}methyl)-4-oxoazetidin-2-yl]oxy}phenyl)acetic acid(4-{[3,3-Diethyl-1-(hydroxy{[1-(4-methylphenyl)butyl]imino}methyl)-4-oxoazetidin-2-yl]oxy}phenyl)acetic acid{4-[(S)-3,3-Diethyl-4-oxo-1-((R)-1-p-tolyl-butylcarbamoyl)-azetidin-2-yloxy]-phenyl}-acetic acid
Database identifiers
- CAS
Properties
Computed structural properties
- XLogP
- 5.7
- Topological polar surface area
- 95.9 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 10
- Heavy atoms
- 34
- Formal charge
- 0
- Complexity
- 706
Chemistry & industry
Applications
DescriptionL 680833 is a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase.
UsesL-680833 is a monocyclic β-lactam inhibitor of human polymorphonuclear leukocyte elastase (PMNE) inhibitor. L-680833 can be used for the study of PMNE-damaged tissue diseases[1].
Suppliers4 total
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
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Compound notes
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