(-)-Nornuciferine
Basic information
- CAS
3153-55-7- Standard SMILES
COc1c(O)cc2c3c1-c1ccccc1C[C@H]3N(C)CC2- InChIKey
AKXOIHNFHOEPHN-CQSZACIVSA-N- Molecular formula
- C18H19NO2
- Average molar mass
- 281.3 g/mol
- Monoisotopic mass
- 281.14157885
Overview
O-Nornuciferine has been reported in Stephania cephalantha, Ziziphus jujuba, and other organisms with data available.
Names & identifiers
- Preferred name
- (-)-Nornuciferine
- IUPAC
- (6aR)-1-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol
- English name
- ORTHO-NORNUCIFERINE
- Molecular formula
- C18H19NO2
- Molecular weight
- 281.35
Names & synonyms
3153-55-7(-)-Nornuciferine2D75P3S5Q6Nornuciferine, (-)-RefChem:1049126O-NornuciferineN-MethylasimilobineAsimilobine, N-methyl-O-demethyl nuciferineMethylasimilobine(6aR)-1-methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol(6aR)-5,6,6a,7-Tetrahydro-1-methoxy-6-methyl-4H-dibenzo[de,g]quinolin-2-ol
Show more names
floribundineORTHO-NORNUCIFERINEO-Nornuciferine, 10 mM in DMSOO-Nornuciferine,Inhibitor,Potassium Channel,KcsA,inhibit,ONornuciferine,O Nornuciferine
(R)-1-Methoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-2-ol4H-Dibenzo(de,g)quinolin-2-ol, 5,6,6a,7-tetrahydro-1-methoxy-6-methyl-, (R)-4H-Dibenzo[de,g]quinolin-2-ol, 5,6,6a,7-tetrahydro-1-methoxy-6-methyl-, (6aR)-CCRIS 38086a-beta-Aporphin-2-ol, 1-methoxy-6a.beta.-Aporphin-2-ol, 1-methoxy-4H-Dibenzo[de,g]quinolin-2-ol, 5,6,6a,7-tetrahydro-1-methoxy-6-methyl-, (R)-(-)-O-Nornuciferine
Database identifiers
- CAS
3153-55-7- PubChem CID
- 197017
- DTXSID
DTXSID10953513- ChEMBL
CHEMBL2316499- UNII
- 2D75P3S5Q6
- Nikkaji
- J410.360B
Properties
Computed structural properties
- XLogP
- 2.6
- Topological polar surface area
- 32.7 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 1
- Heavy atoms
- 21
- Formal charge
- 0
- Complexity
- 387
Physicochemical properties
- Melting point
- 195 · 195-197℃ (ethyl acetate )
- Boiling point
- 451.4 · 451.4±45.0 °C(Predicted)
- Density
- 1.216 · 1.216±0.06 g/cm3(Predicted)
- pka
- 10.12 · 10.12±0.20(Predicted)
- form
- Solid
- color
- White to off-white
Chemistry & industry
Applications
UsesO-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].
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Related reactions
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Compound notes
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