Basic information
- CAS
178481-68-0- Standard SMILES
CN1CCN(c2ccc3nc(-c4ccc5nc(CCCc6ccc(N(CCCl)CCCl)cc6)[nH]c5c4)[nH]c3c2)CC1- InChIKey
PZEAMYHHAKUANN-UHFFFAOYSA-N- Molecular formula
- C32H37Cl2N7
- Average molar mass
- 590.6 g/mol
- Monoisotopic mass
- 589.2487496
Names & identifiers
- Preferred name
- N,N-bis(2-chloroethyl)-4-[3-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]propyl]aniline
- IUPAC
- N,N-bis(2-chloroethyl)-4-[3-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]propyl]aniline
- English name
- Hoechst 33342 analog
- Molecular formula
- C32H37Cl2N7
- Molecular weight
- 590.59
Names & synonyms
178481-68-0N,N-bis(2-chloroethyl)-4-[3-[6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazol-2-yl]propyl]anilineN,N-Bis(2-chloroethyl)-4-(3-(6-(4-methylpiperazin-1-yl)-1H,3'H-[2,5'-bibenzo[d]imidazol]-2'-yl)propyl)anilineCS-1315NCI60_026636Hoechst 33342 analog?C32H37Cl2N7CHEMBL335278orb1706354SCHEMBL6583077SCHEMBL6583083DTXSID60276749
Show more names
Hoechst 33342 analogBenzenamine, N,N-bis(2-chloroethyl)-4-[3-[5-(4-methyl-1-piperazinyl)[2,5'-bi-1H-benzimidazol]-2'-yl]propyl]- (9CI)
MFCD02183866AKOS040744081DA-74246HY-15627MS-30520PD101461F84929T19010
Database identifiers
- CAS
178481-68-0- PubChem CID
- 197366
Properties
Computed structural properties
- XLogP
- 6.6
- Topological polar surface area
- 67.1 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 5
- Rotatable bonds
- 11
- Heavy atoms
- 41
- Formal charge
- 0
- Complexity
- 784
Physicochemical properties
- Boiling point
- 841.2 · 841.2±75.0 °C(Predicted)
- Density
- 1.303 · 1.303±0.06 g/cm3(Predicted)
- solubility
- 25 ℃: · 25℃: DMSO or water Protect from light
- form
- Powder
- pka
- 11.02 · 11.02±0.10(Predicted)
- color
- Off-white to brown
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302-H315-H319-H335
- Precautionary statements
- 261 · P261-P305+P351+P338
- Toxicity
- 5 mmol/L · mnt-ham-ovr 5 mmol/L MUREAV 448,35,2000
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- Toxicity
- mnt-ham-ovr 5 mmol/L MUREAV 448,35,2000
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P305+P351+P338
Chemistry & industry
Applications
UsesHoechst 33342 analog is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Suppliers13 total
AdooQ BioScience, LLC+1 (866) 930-6790 · [email protected]
天津普西唐生物医药科技有限公司010-60605840 · [email protected]
南京百鑫德诺生物科技有限公司025-58849295 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
斯派螺（武汉）药物研发有限公司[email protected]
上海珈得尔化学技术有限公司13564435016 13564435016 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
天津凯利奇生物科技有限公司15076683720 · [email protected]
上海立崎生物医学研究中心18014399201 · [email protected]
Musechem+1-800-259-7612 · [email protected]
上海瀚香生物科技有限公司
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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