Basic information
- CAS
3942-54-9- Standard SMILES
CNC(=O)Oc1ccccc1Cl- InChIKey
ZAGNMMRDHSEOPE-UHFFFAOYSA-N- Molecular formula
- C8H8ClNO2
- Average molar mass
- 185.61 g/mol
- Monoisotopic mass
- 185.02435618
Names & identifiers
- Preferred name
- o-Chlorophenyl methylcarbamate
- IUPAC
- (2-chlorophenyl) N-methylcarbamate
- English name
- CPMC
- Molecular formula
- C8H8ClNO2
- Molecular weight
- 185.61
Names & synonyms
Etrofol2-Chlorophenyl methylcarbamate3942-54-9Hopcide2-chlorophenyl N-methylcarbamateHoppsideO-CHLOROPHENYL METHYLCARBAMATECarbamic acid, methyl-, 2-chlorophenyl esterRo 7-47802-Chlorophenyl-N-methylcarbamateHSDB 2609EINECS 223-524-3
Show more names
CPMCHopsidero7-4780CPMC emulsionetrofol (cpmc)Hopcide emulsiono-chlorophenylmethylcarbamate
BRN 2048887R4I4K15V9BAI3-27692Carbamic acid, methyl-, o-chlorophenyl esterCarbamic acid, N-methyl-, 2-chlorophenyl ester4-06-00-00795 (Beilstein Handbook Reference)O-CHLOROPHENYL METHYLCARBAMATE [HSDB]RefChem:855221
Database identifiers
- CAS
3942-54-9- PubChem CID
- 19841
- DTXSID
DTXSID3058084- UNII
- R4I4K15V9B
- EC Number
- 223-524-3
- Nikkaji
- J8.277E
Properties
Computed structural properties
- XLogP
- 1.6
- Topological polar surface area
- 38.3 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 2
- Heavy atoms
- 12
- Formal charge
- 0
- Complexity
- 163
Experimental & physicochemical properties
SpringerMaterials PropertiesFusion temperature
PesticidesPesticides -> Carbamate Insecticides
LogP1.64
Color/FormWHITE CRYSTALS
SolubilitySOL IN ACETONE, METHANOL, ETHANOL, DIMETHYLFORMAMIDE
Melting Point90-91 °C
Vapor Pressure0.00831 [mmHg]
Physical DescriptionWhite solid; [HSDB]
Physicochemical properties
- Density
- 1.2797 · 1.2797 (rough estimate)
- refractive index
- 1.556 · 1.5560 (estimate)
- FDA UNII
- 4 I4K15V9B · R4I4K15V9B
- EPA Substance Registry System
- 2 · Carbamic acid, methyl-, 2-chlorophenyl ester (3942-54-9)
- TSCA
- TSCA listed
- Hazardous Substances Data
- 3942 · 3942-54-9(Hazardous Substances Data)
Safety & regulation
GHS classification
GHS Classification
Warning
H302: Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Hazard information
Hazards SummaryNo deaths in mice in doses up to 600 mg/kg by skin application; [HSDB] See CARBAMATE INSECTICIDES.
Hazard Classes and CategoriesAcute toxicity (Oral) - Category 4
Safety & protection
Exposure Control and Personal Protection
Biological Exposure Indices (BEI) [ACGIH] - Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Toxicology
Ecotoxicity ValuesTLM: CARP 10.9 PPM/48 HR
Adverse EffectsOther Poison - Carbamate
Non-Human Toxicity Excerpts...MALE MOUSE...DERMAL TOXICITY--NO DEATH UP TO 600 MG/KG.
Antidote and Emergency Treatment
1) ESTABLISH CLEAR AIRWAY & TISSUE OXYGENATION BY ASPIRATION OF SECRETIONS & IF NECESSARY...ASSISTED PULMONARY VENTILATION WITH OXYGEN. DO NOT ADMIN ATROPINE UNTIL SATISFACTORY LEVEL OF OXYGENATION...ACHIEVED. ATROPINE MAY INDUCE VENTRICULAR FIBRILLATION IF VICTIM...SEVERELY ASPHYXIC. /CARBAMATES, CHOLINESTERASE INHIBITORS/
2) ADMIN ATROPINE SULFATE IV, OR IM IF IV INJECTION IS NOT POSSIBLE. ATROPINE PROTECTS END-ORGANS FROM EXCESSIVE CONCN OF ACETYLCHOLINE. IT DOES NOT REACTIVATE CHOLINESTERASE, & EFFECTS OF UNMETABOLIZED TOXICANT MAY APPEAR AS ATROPINIZATION WEARS OFF. /CARBAMATES, CHOLINESTERASE INHIBITORS/
2) IN MODERATELY SEVERE POISONING: ADULT DOSE (INCL CHILDREN OVER 12 YR): 0.4-2.0 MG/KG BODY WT (1.0-5.0 ML OF USUAL 0.4 MG/ML SOLN) REPEATED EVERY 15-30 MIN UNTIL ATROPINIZATION IS ACHIEVED (TACHYCARDIA, FLUSHING, DRY MOUTH, MYDRIASIS). MAINTAIN...BY REPEATED DOSES FOR 2-12 HR... /CARBAMATES, CHOLINESTERASE INHIBITORS/
2) CHILD'S DOSE: 0.01 MG/KG BODY WT (0.05 ML/KG OF USUAL 0.4 MG/ML SOLN) REPEATED EVERY 15-30 MIN UNTIL ATROPINIZATION IS ACHIEVED. IN SEVERE POISONING, USE TWICE THE DOSAGE OF ATROPINE RECOMMENDED ABOVE. /CARBAMATES, CHOLINESTERASE INHIBITORS/
For more Antidote and Emergency Treatment (Complete) data for O-CHLOROPHENYL METHYLCARBAMATE (10 total), please visit the HSDB record page.
Safety data
- tsca
- TSCA listed
- Hazardous Substances Data
- 3942-54-9(Hazardous Substances Data)
Chemistry & industry
Uses & manufacturing
Uses
Formerly used as insecticide on rice; [HSDB]
Farming (Pesticides) [Category: Industry]
FORMERLY A SELECTIVE INSECTICIDE AGAINST SUCKING INSECTS, FOR PLANTHOPPERS AND LEAFHOPPERS ON RICE
U.S. Exports
(1972) No Data
(1975) No Data
U.S. Imports
(1972) No Data
(1975) No Data
U.S. Production(1972) PROBABLY GREATER THAN 4.54X10+5 GRAMS
Methods of ManufacturingFORMERLY BY REACTION OF ORTHO-ISOPROPYLPHENOL AND METHYL ISOCYANATE
Formulations/Preparations
WETTABLE POWDER 50%.
HOPCIDE (CPMC) EMULSIFIABLE CONCN CONTAINS 20% ACTIVE INGREDIENT & HOPCIDE (CPMC) WETTABLE POWDER CONTAINS 20%.
General Manufacturing InformationCarbamic acid, N-methyl-, 2-chlorophenyl ester: INACTIVE
Suppliers6 total
梯希爱（上海）化工贸易有限公司021-61109150 · [email protected]
玺标（上海）科技有限公司18512111473 18512111473 · [email protected]
天津阿尔塔科技有限公司022-6537-8550 15522853686 · [email protected]
SUZHOU SENFEIDA CHEMICAL CO.,LTD+86-0512-83500002 +86-15195660023 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
上海杰股生物科技有限公司021-51698675 · [email protected]
Related reactions
1 records
Compound notes
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