Basic information
- CAS
3776-37-2- Standard SMILES
NCCC[C@H](N)CC(=O)NCCC[C@H](N)CC(=O)NCCC[C@H](N)CC(=O)N[C@@H]1[C@H](O)[C@@H](OC(N)=O)[C@@H](CO)O[C@H]1NC1=NC2C(=O)NCC(O)C2N1- InChIKey
WUJTXMVGXDQPNN-RPRJZONPSA-N- Molecular formula
- C31H58N12O10
- Average molar mass
- 758.9 g/mol
- Monoisotopic mass
- 758.43988609
Overview
streptothricin D has been reported in Streptomyces qinlingensis, Streptomyces, and Streptomyces nojiriensis with data available.
Names & identifiers
- Preferred name
- 2-((3-Amino-6-((3-amino-6-((3,6-diamino-1-hydroxyhexylidene)amino)-1-hydroxyhexylidene)amino)-1-hydroxyhexylidene)amino)-2-deoxy-N-(4,7-dihydroxy-3a,6,7,7a-tetrahydro-3H-imidazo(4,5-c)pyridin-2-yl)-4-O-(hydroxy(imino)methyl)hexopyranosylamine
- IUPAC
- [(2R,3R,4S,5R,6R)-5-[[(3S)-3-amino-6-[[(3S)-3-amino-6-[[(3S)-3,6-diaminohexanoyl]amino]hexanoyl]amino]hexanoyl]amino]-4-hydroxy-2-(hydroxymethyl)-6-[(7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo[4,5-c]pyridin-2-yl)amino]oxan-3-yl] carbamate
- English name
- streptothricin D
- Molecular formula
- C31H58N12O10
- Molecular weight
- 758.88
Names & synonyms
[(2R,3R,4S,5R,6R)-5-[[(3S)-3-amino-6-[[(3S)-3-amino-6-[[(3S)-3,6-diaminohexanoyl]amino]hexanoyl]amino]hexanoyl]amino]-4-hydroxy-2-(hydroxymethyl)-6-[(7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo[4,5-c]pyridin-2-yl)amino]oxan-3-yl] carbamateDTXSID60958811((2R,3R,4S,5R,6R)-5-(((3S)-3-amino-6-(((3S)-3-amino-6-(((3S)-3,6-diaminohexanoyl)amino)hexanoyl)amino)hexanoyl)amino)-4-hydroxy-2-(hydroxymethyl)-6-((7-hydroxy-4-oxo-1,3a,5,6,7,7a-hexahydroimidazo(4,5-c)pyridin-2-yl)amino)oxan-3-yl) carbamateRefChem:1060505DTXCID501386705((2R,3R,4S,5R,6R)-5-(((3S)-3-amino-6-(((3S)-3-amino-6-(((3S)-3,6-diaminohexanoyl)amino)hexanoyl)amino)hexanoyl)amino)-4-hydroxy-2-(hydroxymethyl)-6-((E)-(7-hydroxy-4-oxo-3,3a,5,6,7,7a-hexahydro-1H-imidazo(4,5-c)pyridin-2-ylidene)amino)oxan-3-yl) carbamate2-((3-Amino-6-((3-amino-6-((3,6-diamino-1-hydroxyhexylidene)amino)-1-hydroxyhexylidene)amino)-1-hydroxyhexylidene)amino)-2-deoxy-N-(4,7-dihydroxy-3a,6,7,7a-tetrahydro-3H-imidazo(4,5-c)pyridin-2-yl)-4-O-(hydroxy(imino)methyl)hexopyranosylamine
Properties
Computed structural properties
- XLogP
- -7.3
- Topological polar surface area
- 379 Ų
- Hydrogen bond donors
- 14
- Hydrogen bond acceptors
- 15
- Rotatable bonds
- 23
- Heavy atoms
- 53
- Formal charge
- 0
- Complexity
- 1,260
Physicochemical properties
- Density
- 1.67 · 1.67±0.1 g/cm3(Predicted)
- pka
- 12.62 · 12.62±0.70(Predicted)
Chemistry & industry
Applications
DescriptionRacemomycin B is a beta-lysine rich streptothricin antibiotic.
UsesRacemomycin B (229-B; Streptothricin D), the main component from Streptomyces lavendulae OP-2, is a streptothricin antibiotic containing three β-lysine groups. RM-B exhibits antimicrobial activity against plant pathogenic microorganisms and effectively inhibits the growth of Brassica rapa L. roots at 50 ppm. RM-B showed a minimum inhibitory concentration (MIC) of 0.4 μg/ml against Pseudomonas syringae pv. tabaci IFO-3508 and a MIC range of 0.1-2.0 μg/ml against six strains of Fusarium oxysporum, showing stronger antimicrobial activity than RM-A and RM-C. The biological activity of racemomycin compounds increases with the increase in the number of β-lysine groups.
Suppliers3 total
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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