Basic information
- CAS
4350-07-6- Standard SMILES
N[C@H](Cc1c[nH]c2ccc(O)cc12)C(=O)O- InChIKey
LDCYZAJDBXYCGN-SECBINFHSA-N- Molecular formula
- C11H12N2O3
- Average molar mass
- 220.22 g/mol
- Monoisotopic mass
- 220.08479225
Overview
5-hydroxy-D-tryptophan is the D-enantiomer of 5-hydroxytryptophan. It is a D-alpha-amino acid, a 5-hydroxytryptophan and a D-tryptophan derivative. It is an enantiomer of a 5-hydroxy-L-tryptophan.
Names & identifiers
- Preferred name
- 5-Hydroxy-D-tryptophan
- IUPAC
- (2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
- English name
- D-2-Amino-3-(5-hydroxyindolyl)propionic acid
- Molecular formula
- C11H12N2O3
- Molecular weight
- 220.22
Names & synonyms
5-hydroxy-D-tryptophanD-5-Hydroxytryptophan5-Hydroxytryptophan D-form(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acidTryptophan, 5-hydroxy-, D-0ZQ5SQ239QUNII-0ZQ5SQ239Q5-HYDROXYTRYPTOPHAN, D-CHEBI:43186DTXSID401958635-HYDROXYTRYPTOPHAN D-FORM [MI]RefChem:102852
Show more names
5-hydroxy-d-tryptophaTryptophan Impurity 42D-2-Amino-3-(5-hydroxyindolyl)propionic acid(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propionic acid(2R)-2-azanyl-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
DTXCID80118354(2R)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid;5-hydroxy-D-tryptophan636-955-04350-07-6(R)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acidD-Tryptophan, 5-hydroxy-D-5-HTPMFCD00069709
Database identifiers
- CAS
4350-07-6- PubChem CID
- 199528
Properties
Computed structural properties
- XLogP
- -1.2
- Topological polar surface area
- 99.3 Ų
- Hydrogen bond donors
- 4
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 3
- Heavy atoms
- 16
- Formal charge
- 0
- Complexity
- 272
Physicochemical properties
- Melting point
- 270 C · 270C
- Boiling point
- 520.6 · 520.6±50.0 °C(Predicted)
- Density
- 1.484 · 1.484±0.06 g/cm3(Predicted)
- storage temp.
- 2 · Sealed in dry,2-8°C
- pka
- 2.22 · 2.22±0.10(Predicted)
- FDA UNII
- 0 ZQ5SQ239Q · 0ZQ5SQ239Q
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 332 · H332-H312
- Precautionary statements
- 261 · P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501
- Hazard Codes
- Xn,Xi
- Risk Statements
- 20 · 20/21-20/21/22-36/37/38-65
- Safety Statements
- 26 · 26-36
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
Warning
H312 (100%): Harmful in contact with skin [Warning Acute toxicity, dermal]
P261, P271, P280, P302+P352, P304+P340, P317, P321, P362+P364, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesAcute Tox. 4 (100%)
Safety data
- risk_code
- 20/21-20/21/22-36/37/38-65
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- hazard_code
- Xn,Xi
- safety_code
- 26-36
- Hazard statements
- H332-H312
- Precautionary statements
- P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501
Chemistry & industry
Applications
UsesD-5-Hydroxytryptophan (D-5-HTP) is the D-isomer of 5-HTP and can be isolated from DL-5-hydroxytryptophan by continuous separation. Compared with intraperitoneal administration of L-5-Hydroxytryptophan, which can induce dose-dependent backward walking behavior in mice, D-5-Hydroxytryptophan has no significant effect on mouse behavior and is a negative control. D-5-Hydroxytryptophan is also a 5-HT ligand, capable of binding to the 5-HT site with affinity in the micromolar range[1][2][3].
Suppliers7 total
苏州爱玛特生物科技有限公司0512-56316828 4008675858 · [email protected]
江苏艾康生物医药研发有限公司025-66028182 17714375163 · [email protected]
BOC Sciences+1-631-485-4226 · [email protected]
Nextpeptide Inc+86-0571-81612335 +8613336028439 · [email protected]
Jilin Chinese Academy of Sciences-yanshen Technology18143011203 · [email protected]
DAYANG CHEM (HANGZHOU) CO.,LTD+86-88938639 +86-17705817739 · [email protected]
DONBOO AMINO ACID COMPANY13063595538 · [email protected]
Additional notes
DefinitionChEBI: The D-enantiomer of 5-hydroxytryptophan.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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