Basic information
- CAS
2079-78-9- Standard SMILES
C[N+](C)(C)CCCCCC[N+](C)(C)C.O=C([O-])[C@H](O)[C@@H](O)C(=O)O.O=C([O-])[C@H](O)[C@@H](O)C(=O)O- InChIKey
FBKYPSXTNBQAJW-WBPXWQEISA-L- Molecular formula
- C20H40N2O12
- Average molar mass
- 500.5 g/mol
- Monoisotopic mass
- 500.25812472
Overview
See also: Hexamethonium (has active moiety).
Names & identifiers
- Preferred name
- Hexamethonium Tartrate
- IUPAC
- bis((2R,3R)-2,3,4-trihydroxy-4-oxobutanoate);trimethyl-[6-(trimethylazaniumyl)hexyl]azanium
- English name
- hexamethonium tartrate
- Molecular formula
- C16H34N2O6
- Molecular weight
- 350.45096
Names & synonyms
Hexamethonium tartrateEsotensylEsoniumVegolysen-THexamethonium bitartrate4U6FTZ422JRefChem:146070218-207-12079-78-9(2R,3R)-2,3,4-trihydroxy-4-oxobutanoate;trimethyl-[6-(trimethylazaniumyl)hexyl]azaniumUNII-4U6FTZ422JHexamethonium tartrate [BAN]
Show more names
Vegolysen T
EINECS 218-207-1Hexamethylenebistrimethylammonium di(hydrogen tartrate)Tartaric acid, hexamethylenebis(trimethylammonium)salt (2:1)HEXAMETHONIUM TARTRATE [MI]HEXAMETHONIUM TARTRATE [MART.]NS00081438Q27260508AMMONIUM, HEXAMETHYLENEBIS(TRIMETHYL-, TARTRATE (1:2)
Database identifiers
- CAS
2079-78-9- PubChem CID
- 20055331
- ChEMBL
CHEMBL2146097- UNII
- 4U6FTZ422J
- EC Number
- 218-207-1
Properties
Computed structural properties
- Topological polar surface area
- 236 Ų
- Hydrogen bond donors
- 6
- Hydrogen bond acceptors
- 12
- Rotatable bonds
- 11
- Heavy atoms
- 34
- Formal charge
- 0
- Complexity
- 268
Physicochemical properties
- FDA UNII
- 4 U6FTZ422J · 4U6FTZ422J
Chemistry & industry
Pharmacology
MeSH Pharmacological Classification
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Agents having as their major action the interruption of neural transmission at nicotinic receptors on postganglionic autonomic neurons. Because their actions are so broad, including blocking of sympathetic and parasympathetic systems, their therapeutic use has been largely supplanted by more specific drugs. They may still be used in the control of blood pressure in patients with acute dissecting aortic aneurysm and for the induction of hypotension in surgery.
Drugs that bind to nicotinic cholinergic receptors (RECEPTORS, NICOTINIC) and block the actions of acetylcholine or cholinergic agonists. Nicotinic antagonists block synaptic transmission at autonomic ganglia, the skeletal neuromuscular junction, and at central nervous system nicotinic synapses.
Suppliers3 total
陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Related reactions
0 records
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Compound notes
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