Basic information
- CAS
442-16-0- Standard SMILES
CCOc1ccc2nc3cc(N)ccc3c(N)c2c1- InChIKey
CIKWKGFPFXJVGW-UHFFFAOYSA-N- Molecular formula
- C15H15N3O
- Average molar mass
- 253.3 g/mol
- Monoisotopic mass
- 253.12151211
Overview
Ethacridine is a member of acridines.
Names & identifiers
- Preferred name
- Ethacridine
- IUPAC
- 7-ethoxyacridine-3,9-diamine
- English name
- 2-Ethoxy-6,9-diaminoacridine
- Molecular formula
- C15H15N3O
- Molecular weight
- 253.3
Names & synonyms
ETHACRIDINE442-16-06,9-Diamino-2-ethoxyacridineAethacridinumEtacridinaEthacridinum2,5-Diamino-7-ethoxyacridineOphosept3,9-Acridinediamine, 7-ethoxy-WIX85M1A6RNSC-163296DTXSID2048402
Show more names
ACRINOLRIVANOLEtakridinEthacrindine2-Ethoxy-6,9-acridinediamine7-Ethoxy-3,9-acridinediamine2-Ethoxy-6,9-diaminoacridine7-ETHOXY-ACRIDINE-3,9-DIAMINE
Monohydrate, EthacridineRefChem:138010acrinolum (for the lactate)2,5 Diamino 7 ethoxyacridineMonohydrate Ethacridine LactateDTXCID0028375B05CA08D08AA01
Database identifiers
- CAS
442-16-0- PubChem CID
- 2017
- DTXSID
DTXSID2048402- ChEMBL
CHEMBL94007- ChEBI
CHEBI:135032- UNII
- WIX85M1A6R
- EC Number
- 207-130-9
- Nikkaji
- J2.045A
Properties
Computed structural properties
- XLogP
- 2.5
- Topological polar surface area
- 74.2 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 2
- Heavy atoms
- 19
- Formal charge
- 0
- Complexity
- 312
Experimental & physicochemical properties
Drugs
Pharmaceuticals
Pharmaceuticals -> Antibiotics
Physicochemical properties
- Melting point
- 226 ° · 226°
- Boiling point
- 396.5 °C · 396.5°C (rough estimate)
- Density
- 1.0966 · 1.0966 (rough estimate)
- refractive index
- 1.57 · 1.5700 (estimate)
- storage temp.
- 2 · 2-8°C
- pka
- 11.22 · 11.22±0.10(Predicted)
- FDA UNII
- 85 M1A6R · WIX85M1A6R
- Symbol(GHS)
- 7 · GHS07
- Signal word
- Warning
- Hazard statements
- 302 · H302
- Precautionary statements
- 264 · P264-P270-P301+P312-P330-P501
- REACH Registrations
- Active
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 4.9% (2 of 41) of reports.
Warning
H302 (95.1%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 41 reports by companies from 2 notifications to the ECHA C&L Inventory.
Hazard information
Regulatory InformationREACH registered substance: Ethacridine (EC: 207-130-9)
Other Safety InformationIMAP assessments - 3,9-Acridinediamine, 7-ethoxy-: Human health tier I assessment
Hazard Classes and CategoriesAcute Tox. 4 (95.1%)
Safety data
- Signal word
- Warning
- Symbol(GHS)
- GHS07
- Hazard statements
- H302
- REACH Registrations
- Active
- Precautionary statements
- P264-P270-P301+P312-P330-P501
Chemistry & industry
Pharmacology
MeSH Pharmacological ClassificationSubstances used on humans and other animals that destroy harmful microorganisms or inhibit their activity. They are distinguished from DISINFECTANTS, which are used on inanimate objects.
Uses & manufacturing
UsesUse (kg; approx.) in Germany (2009): >1000
Applications
Uses7-ethoxyacridine-3,9-diamine is used in biological studies for cancer regression by inducing a regeneration-like response by activating expression and/or function of YAP and/or TAZ.
Upstream & downstream products
Upstream raw materials
Suppliers23 total
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
LGM Pharma1-(800)-881-8210 · [email protected]
InvivoChem中国13549236410 · [email protected]
上海遐瑞医药科技有限公司+86 21 61551611
PT CHEM GROUP LIMITED+86-85511178; +86-85511178 · [email protected]
Alfa Chemistry1-516-6625404 · [email protected]
Alfa Chemistry+1-5166625404 · [email protected]
山东盛之源生物科技有限公司13969162569
Shandong Shengzhiyuan Biotechnology Co., LTD+86-15064083436 +86-15854929067 · [email protected]
上海麦克林生化科技股份有限公司50706066 15221275939 · [email protected]
苏州莱惠生物技术有限公司180-1316-0973
陕西缔都医药化工有限公司029-81154043 17391733319 · [email protected]
杭州洁汉化工有限公司+86-571-86217390; +8618058761490 · [email protected]
江苏艾康生物医药研发有限公司025-58859352 19370895928 · [email protected]
武汉峰耀同辉化学制品有限公司027-87466105 15377573527 · [email protected]
广州贝尔卡生物科技有限公司+86-18665676617
湖北摩科化学有限公司18627753421; 18627756402 · [email protected]
BOC Sciences+1-631-485-4226 · [email protected]
TargetMol中国（陶术生物）15002134094 · [email protected]
Dideu Industries Group Limited+8617392712697 · [email protected]
河南威梯希化工科技有限公司0371-55135753 18003832934 · [email protected]
广州优南科技有限公司020-82000279 18988941452 · [email protected]
Additional notes
DefinitionChEBI: Ethacridine is a member of acridines.
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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