Basic information
- CAS
4292-10-8- Standard SMILES
CCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(=O)[O-]- InChIKey
MRUAUOIMASANKQ-UHFFFAOYSA-N- Molecular formula
- C19H38N2O3
- Average molar mass
- 342.5 g/mol
- Monoisotopic mass
- 342.28824308
Overview
The CIR Expert Panel concluded that the following ingredients are safe in cosmetics as long as they are formulated to be non-sensitizing, which may be based on a QRA...Lauramidopropyl Betaine...
Names & identifiers
- Preferred name
- Lauramidopropylbetaine
- IUPAC
- 2-[3-(dodecanoylamino)propyl-dimethylazaniumyl]acetate
- English name
- Lauramidopropyl betaine
- Molecular formula
- C19H38N2O3
- Molecular weight
- 342.52
Names & synonyms
4292-10-8LAURAMIDOPROPYL BETAINElauramidopropylbetaineAmphitol 20ABN-Laurylamidopropyl-N,N-dimethylbetaineMACKAM DAB23D6XVI233MACKAM LMB-FNSC-8191CHEBI:63555NSC81911-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-((1-oxododecyl)amino)-, inner salt
Show more names
2-[3-(dodecanoylamino)propyl-dimethylazaniumyl]acetate(carboxymethyl)dimethyl-3-[(1-oxododecyl)amino]propylammonium hydroxideAMphosol LBDehyton L 12Obazoline LABObazoline CABAnpholex LB 2
1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[(1-oxododecyl)amino]-, inner saltRefChem:10883711-Propanaminium, N-(Carboxymethyl)-N,N-Dimethyl-3-((1-Oxododecyl)Amino)-224-292-6(2-(3-(dodecanoylamino)propyl)triazan-2-ium-2-yl)acetate86438-79-1Lauroylamide propylbetaineAmphoteric L
Database identifiers
- CAS
4292-10-8、61789-40-0、86438-79-1- PubChem CID
- 20280
- DTXSID
DTXSID4041282- ChEMBL
CHEMBL1231297- UNII
- 23D6XVI233
- EC Number
- 224-292-6、617-861-9
- Nikkaji
- J205.686K
Properties
Computed structural properties
- XLogP
- 5.4
- Topological polar surface area
- 69.2 Ų
- Hydrogen bond donors
- 1
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 15
- Heavy atoms
- 24
- Formal charge
- 0
- Complexity
- 338
Experimental & physicochemical properties
Cosmetics
Cosmetic ingredients (Lauramidopropyl Betaine) -> CIR (Cosmetic Ingredient Review)
Personal care product
Viscosity controlling; Foam boosting; Surfactant; Hair conditioning; Skin conditioning; Antistatic; Cleansing
Physicochemical properties
- Melting point
- 128 °C · >128°C (dec.)
- Density
- 1.15 · 1.15[at 20℃]
- vapor pressure
- 0.31 Pa · 0.31Pa at 20℃
- storage temp.
- -20 °C · Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 250 mg/L · 250mg/L at 20℃
- Stability
- Hygroscopic
- Cosmetics Ingredients Functions
- SURFACTANT - FOAM BOOSTINGANTISTATICHAIR CONDITIONINGVISCOSITY CONTROLLINGCLEANSINGSURFACTANT - CLEANSINGSKIN CONDITIONING
- Cosmetic Ingredient Review (CIR)
- Lauramidopropyl betaine (4292-10-8)
- InChI
- InChI=1S/C19H38N2O3/c1-4-5-6-7-8-9-10-11-12-14-18(22)20-15-13-16-21(2,3)17-19(23)24/h4-17H2,1-3H3,(H-,20,22,23,24)
- InChIKey
- MRUAUOIMASANKQ-UHFFFAOYSA-N
- SMILES
- [N+](C)(C)(CC(=O)[O-])CCCNC(=O)CCCCCCCCCCC
- LogP
- 3.54 at · 3.54 at 20℃
- EWG's Food Scores
- 1 · 1-3
- FDA UNII
- 23 D6XVI233 · 23D6XVI233
- EPA Substance Registry System
- 1 · 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[(1-oxododecyl)amino]-, inner salt (4292-10-8)
- Symbol(GHS)
- 5 · GHS05
- Signal word
- Danger
- Hazard statements
- 412 · H412-H318
- Precautionary statements
- 280 · P280-P305+P351+P338-P310-P273-P501
- TSCA
- TSCA listed
- REACH Registrations
- Active
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
GHS classification
GHS Classification
This chemical does not meet GHS hazard criteria for 0.7% (5 of 714) of reports.
Danger
H315 (70.2%): Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P273, P280, P302+P352, P305+P351+P338, P305+P354+P338, P317, P321, P332+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 714 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
This chemical does not meet GHS hazard criteria for 20% (1 of 5) of reports.
Hazard information
Regulatory Information
Chemical: 1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[(1-oxododecyl)amino]-, inner salt
Status: Active Update: 15-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/12545
1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-(1-oxododecyl)amino-, inner salt: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Mirataine CB: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
EPA Safer ChemicalChemical: Lauramidopropyl betaine
Hazard Classes and Categories
Eye Dam. 1 (80%)
Skin Irrit. 2 (70.2%)
Hazardous to the aquatic environment (Acute) - Category 2
Toxicology
Toxicity Summary
The CIR Expert Panel concluded that the following ingredients are safe in cosmetics as long as they are formulated to be non-sensitizing, which may be based on a QRA...Lauramidopropyl Betaine...
Safe for use in cosmetics, with qualifications
Safety data
- tsca
- TSCA listed
- Signal word
- Danger
- Symbol(GHS)
- GHS05
- Hazard statements
- H412-H318
- REACH Registrations
- Active
- Precautionary statements
- P280-P305+P351+P338-P310-P273-P501
Chemistry & industry
Uses & manufacturing
UsesCIR ingredient: Lauramidopropyl Betaine
Household ProductsInformation on 10 consumer products that contain Lauramidopropyl betaine in the following categories is provided:
Use Classification
EPA Safer Chemical Functional Use Classes -> Surfactants
Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern
Cosmetics -> Viscosity controlling; Foam boosting; Surfactant; Hair conditioning; Skin conditioning; Antistatic; Cleansing
General Manufacturing Information1-Propanaminium, N-(carboxymethyl)-N,N-dimethyl-3-[(1-oxododecyl)amino]-, inner salt: ACTIVE
Applications
DescriptionLauramidopropyl betaine is a new type of special amphoteric surfactant, which belongs to the same series as lauramidopropyl betaine, and is a modified derivative of alkyl betaine. Lauramidopropyl betaine has the characteristics of temperature resistance, acid and alkali resistance, good salt resistance, wide isoelectric point and strong viscoelasticity, etc. It is widely used in oil field oil repelling, leather, daily chemical industry and other fields. As a good viscoelastic surfactant applied to the substrate acidification of oilfield, it can effectively reduce the oil/water interfacial tension and improve the recovery rate of tertiary oil recovery. Also it can be used as conditioning agent, wetting agent, bactericide, antistatic agent, emulsifier, thickener and in self-steering acid system for carbonate acidification.
UsesLauroylamide Propylbetaine is used cosmetic and hair compositions of enhanced viscosity and clarity.
Suppliers100 total
郑州阿尔法化工有限公司+86-18530059196 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
Career Henan Chemica Co+86-0371-86658258 +86-13203830695 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
广州纳珑化工有限公司13192879270; 13192879270 · [email protected]
山东安米化工科技有限公司0533-0533-2115911 13396436781 · [email protected]
湖北鑫杰成化工科技有限公司13554075426 · [email protected]
武汉欣扬瑞和化学科技有限公司153-07155313 15307155313 · [email protected]
上海毕得医药科技股份有限公司400-1647117 13681763483 · [email protected]
杭州埃肯新材料有限公司15258847994 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
河北展药生物科技有限公司15369953316 +8615369953316 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Hebei Yanxi Chemical Co., Ltd.+86-17531190177 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
上海晶抗生物工程有限公司021-54721350 13524668266 · [email protected]
上海颖心实验室设备有限公司021-59178156 17002132182 · [email protected]
武汉市聚舜化工有限公司027-02783261126 18971318572 · [email protected]
太原市瑞和丰科贸有限公司+86 351 7031519 · [email protected]
湖北兴琰新材料科技有限公司13129948835 · [email protected]
广东方信生物科技有限公司0751-2838688 13376594225 · [email protected]
河北缤享新材料科技有限公司+8618633865755 · [email protected]
上海钰康生物科技有限公司+86-18930848214 +86-021-56762820 · [email protected]
上海泰坦科技股份有限公司4006009262 13023226327 · [email protected]
湖北广奥生物科技有限公司027-02702759223056 18162699093 · [email protected]
河北茹麒科技有限公司176-03256889 17603256889 · [email protected]
Hebei shenghao import and export trade co. LTD+8618431136903
山东西亚化学有限公司13355009207 13355009207 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
Xiamen AmoyChem Co., Ltd+86-86-5926051114 · [email protected]
湖南汇百侍生物科技有限公司0731-85526065 13308475853 · [email protected]
南京维奥化工有限公司Please Send Email 18652950785 · [email protected]
上海源叶生物科技有限公司18916372613 · [email protected]
艾科试剂4008-755-333 18080918076 · [email protected]
上海遐瑞医药科技有限公司+86 21 61551611
武汉卡诺斯科技有限公司153-37111468 15337111468 · [email protected]
成都零六生物科技有限公司400-1166-196 13458535857 · [email protected]
湖南华腾制药有限公司400-8592883 15367835770 · [email protected]
上海创赛科技有限公司400-6087598 15021221957 · [email protected]
上海麦克林生化科技股份有限公司15221275939 15221275939 · [email protected]
武汉贝乐叶生物医药科技有限公司18086118078 · [email protected]
湖北巨胜科技有限公司027-59599241 18871490274 · [email protected]
池州凯隆进出口贸易有限公司[email protected]
上海昕凯医药科技有限公司21-619849051-1 18521059765 · [email protected]
上海谱振生物科技有限公司4001650900 13817534909 · [email protected]
广东翁江化学试剂有限公司0751-2815987 13927875076 · [email protected]
厦门志信化学有限公司+86-5922680277 +86-13806087780 · [email protected]
Related reactions
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No reaction records under the current filter.
Compound notes
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