Basic information
- CAS
168836-03-1- Standard SMILES
Cc1cc2ncc(-c3ccc(O)c(O)c3)nc2cc1C- InChIKey
GRLICEOJIPVEEY-UHFFFAOYSA-N- Molecular formula
- C16H14N2O2
- Average molar mass
- 266.29 g/mol
- Monoisotopic mass
- 266.10552769
Overview
Tyrphostin AG 1433 is a member of the Tyrphostin family of tyrosine kinase inhibitors that selectively inhibits platelet-derived growth factor beta-receptor kinase and angiogenesis. (NCI)
Names & identifiers
- Preferred name
- 4-(6,7-Dimethylquinoxalin-2-yl)benzene-1,2-diol
- IUPAC
- 4-(6,7-dimethylquinoxalin-2-yl)benzene-1,2-diol
- English name
- TYRPHOSTIN AG 1433
- Molecular formula
- C16H15ClN2O2
- Molecular weight
- 302.76
Names & synonyms
Tyrphostin AG1433168835-90-34-(6,7-dimethylquinoxalin-2-yl)benzene-1,2-diol168836-03-1Tyrphostin AG 1433ag14332-(3,4-dihydroxyphenyl)-6,7-dimethylquinoxalineTyrphostin AG1433 (hydrochloride)SU1433 (hydrochloride); AG1433 (hydrochloride)Tyrphostin AG-14334-(6,7-Dimethylquinoxalin-2-yl)benzene-1,2-diol hydrochlorideTyrphostin AG1433?
Show more names
SU 1433AG 14332-(3',4'-DIHYDROXYPHENYL)-6,7-DIMETHYLQUINOXALINE
4-(6,7-dimethyl-1,4-dihydroquinoxalin-2-yl)cyclohexa-3,5-diene-1,2-dioneCHEMBL420364orb1308979SCHEMBL2156854SCHEMBL30482895BDBM17748DTXSID80417738FVWJXPSCXNQKCW-UHFFFAOYSA-N
Database identifiers
- CAS
168836-03-1- PubChem CID
- 2050
- DTXSID
DTXSID80417738- ChEMBL
CHEMBL420364
Properties
Computed structural properties
- XLogP
- 2.9
- Topological polar surface area
- 66.2 Ų
- Hydrogen bond donors
- 2
- Hydrogen bond acceptors
- 4
- Rotatable bonds
- 1
- Heavy atoms
- 20
- Formal charge
- 0
- Complexity
- 338
Physicochemical properties
- storage temp.
- 2 · 2-8°C
- color
- pale yellow
- Hazard Codes
- Xi
- Risk Statements
- 36 · 36/37/38
- Safety Statements
- 26 · 26-36
- WGK Germany
- 1 · 1
Safety & regulation
Safety information is for reference only and does not replace the supplier’s Safety Data Sheet (SDS), applicable regulations, or professional assessment.
Safety data
- wgk
- 1
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
Chemistry & industry
Applications
UsesTyrphostin AG 1433 is an inhibitor of PDGFR-β, Flk-1, and angiogenesis.
Suppliers5 total
杭州摩库生物医药科技有限公司+86-057181025280; +8617767106207 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
上海陶术生物科技股份有限公司13564774135 · [email protected]
TargetMol中国（陶术生物）4008200310 15002144251 · [email protected]
Related reactions
0 records
No reaction records under the current filter.
Compound notes
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